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给运动医学专业人员的轴性脊柱关节炎管理最新进展

An update on the management of axial spondyloarthritis for sports medicine professionals.

作者信息

Danve Abhijeet, Magrey Marina, Deodhar Atul

机构信息

Rheumatology, Yale School of Medicine, 300 Cedar Street, TACS-525, New Haven, CT, 06520, USA.

University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.

出版信息

BMC Sports Sci Med Rehabil. 2024 Oct 7;16(1):211. doi: 10.1186/s13102-024-00998-z.

Abstract

BACKGROUND

Axial spondyloarthritis (axSpA) is a chronic inflammatory disease which mainly affects the spine and sacroiliac joints, causing longstanding back pain, stiffness, and limited mobility. AxSpA is an underrecognized disease in non-rheumatology practices because of its heterogeneous clinical features that may be difficult to identify.

MAIN BODY

Sports medicine practitioners are well positioned to suspect and recognize axSpA among their patients with chronic back pain and refer them to a rheumatologist. Early referral to a rheumatologist is important for timely diagnosis, prompt treatment, and improved long-term outcomes for patients with axSpA. Physical therapy and nonsteroidal anti-inflammatory drugs (NSAIDs) remain the first-line treatment for and the cornerstone of axSpA management. For patients with inadequate response to or intolerance of NSAIDs, biologic disease-modifying antirheumatic drugs (bDMARDs) and targeted synthetic (ts) DMARDs are indicated. These drugs can reduce pain, inflammation, fatigue, and disability and can improve health-related quality of life. The goal of this review is to improve awareness of axSpA among sports medicine practitioners and other non-rheumatologists so that these providers ensure timely referral of patients with suspected axSpA to rheumatologists for appropriate treatment and better outcomes. We also provide an update on current treatment possibilities for axSpA and describe how rheumatologists use treatment guidelines and disease activity measures to identify and optimally treat patients with active axSpA.

CONCLUSION

Sports medicine practitioners have an excellent opportunity to identify patients with suspected axSpA and refer them to rheumatologists in a timely manner, as well as monitor symptoms among patients diagnosed with axSpA to identify inadequately controlled disease.

摘要

背景

轴性脊柱关节炎(axSpA)是一种慢性炎症性疾病,主要影响脊柱和骶髂关节,导致长期背痛、僵硬和活动受限。由于其临床特征具有异质性,可能难以识别,axSpA在非风湿病诊疗实践中未得到充分认识。

主体

运动医学从业者有条件在慢性背痛患者中怀疑并识别axSpA,并将他们转诊给风湿病专家。早期转诊给风湿病专家对于axSpA患者的及时诊断、迅速治疗以及改善长期预后很重要。物理治疗和非甾体抗炎药(NSAIDs)仍然是axSpA管理的一线治疗方法和基石。对于对NSAIDs反应不足或不耐受的患者,应使用生物改善病情抗风湿药(bDMARDs)和靶向合成(ts)DMARDs。这些药物可以减轻疼痛、炎症、疲劳和残疾,并可以改善健康相关生活质量。本综述的目的是提高运动医学从业者和其他非风湿病专家对axSpA的认识,以便这些医疗服务提供者确保将疑似axSpA的患者及时转诊给风湿病专家进行适当治疗并获得更好的治疗效果。我们还提供了axSpA当前治疗可能性的最新信息,并描述了风湿病专家如何使用治疗指南和疾病活动度测量方法来识别和优化治疗活动性axSpA患者。

结论

运动医学从业者有绝佳机会识别疑似axSpA的患者并及时将他们转诊给风湿病专家,以及监测已诊断为axSpA的患者的症状,以识别控制不佳的疾病。

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