Weiss Ram, Raz Itamar
Harefuah. 2007 Dec;146(12):939, 998.
Ketoacidosis is a common condition in patients with new onset type 1 diabetes and remains a major reason for hospitalization of those with established disease. The major cause of mortality in ketoacidosis is cerebral edema. Although rarely diagnosed on a clinical basis, cerebral edema may have subtle manifestations and is probably under-diagnosed. Novel insights into the underlying pathophysiology of cerebral edema associated with ketoacidosis may help us treat this life threatening condition and prevent the low, yet significant, mortality associated with it.
酮症酸中毒是新发1型糖尿病患者的常见病症，并且仍然是已确诊患者住院治疗的主要原因。酮症酸中毒的主要死亡原因是脑水肿。尽管临床上很少诊断出脑水肿，但它可能有细微的表现，很可能未得到充分诊断。对与酮症酸中毒相关的脑水肿潜在病理生理学的新见解可能有助于我们治疗这种危及生命的病症，并预防与之相关的虽低但显著的死亡率。
