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血管内腹主动脉瘤修复术的肾脏后果

Renal consequences of endovascular abdominal aortic aneurysm repair.

作者信息

Walsh Stewart R, Tang Tjun Y, Boyle Jonathan R

机构信息

Cambridge Vascular Research Unit, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation, Hills Road, Cambridge, UK.

出版信息

J Endovasc Ther. 2008 Feb;15(1):73-82. doi: 10.1583/07-2299.1.

Abstract

Endovascular aneurysm repair (EVAR) of abdominal aortic aneurysm (AAA) is less invasive and has a lower operative mortality than conventional surgery. The relationship between renal function and outcome following open AAA repair has been extensively investigated, but less work has been undertaken with respect to renal function and outcome after EVAR. We reviewed the literature (Medline and PubMed databases) between 1991 and 2007 to investigate the relationship between EVAR and renal dysfunction. Our review found that perioperative renal dysfunction is attenuated by EVAR. However, dialysis rates after EVAR are similar to those after open surgery. EVAR patients develop progressive deterioration in renal function over time. The etiology is unclear and probably multifactorial, involving embolization, contrast media, and graft misplacement. The effect of transrenal endograft fixation on long-term renal function is unknown, but the technique may be associated with a significantly increased risk of renal infarction. The etiology of the renal injury during and after EVAR needs further evaluation, and techniques aimed at renal preservation should be pursued.

摘要

腹主动脉瘤(AAA)的血管内动脉瘤修复术(EVAR)比传统手术侵入性小,手术死亡率更低。开放性AAA修复术后肾功能与预后的关系已得到广泛研究,但关于EVAR术后肾功能与预后的研究较少。我们回顾了1991年至2007年期间的文献(Medline和PubMed数据库),以研究EVAR与肾功能障碍之间的关系。我们的综述发现,EVAR可减轻围手术期肾功能障碍。然而,EVAR后的透析率与开放手术后相似。EVAR患者的肾功能会随着时间的推移而逐渐恶化。其病因尚不清楚,可能是多因素的,包括栓塞、造影剂和移植物放置不当。经肾内移植物固定对长期肾功能的影响尚不清楚,但该技术可能与肾梗死风险显著增加有关。EVAR期间及术后肾损伤的病因需要进一步评估,应探索旨在保护肾脏的技术。

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