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Effects of silymarin (hepatoprotector) and succinic acid (bioenergy regulator) on metabolic disorders in experimental diabetes mellitus.

作者信息

Vengerovskii A I, Khazanov V A, Eskina K A, Vasilyev K Yu

机构信息

Department of Pharmacology, Siberian State Medical University, Tomsk.

出版信息

Bull Exp Biol Med. 2007 Jul;144(1):53-6. doi: 10.1007/s10517-007-0252-2.

DOI:10.1007/s10517-007-0252-2
PMID:18256751
Abstract

Silymarin (70 mg/kg) and succinic acid (50 mg/kg) reduce blood glucose and cholesterol concentrations, inhibit LPO, and correct oxidative phosphorylation disturbances in liver mitochondria in experimental diabetes mellitus induced by injection of streptozotocin (65 mg/kg) in rats.

摘要

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