Murakami Yoshiaki, Uemura Kenichiro, Sudo Takeshi, Hayashidani Yasuo, Hashimoto Yasushi, Nakagawa Naoya, Ohge Hiroki, Sueda Taijiro
Department of Surgery, Division of Clinical Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Hiroshima, 734-8551, Japan.
J Gastrointest Surg. 2008 Jun;12(6):1081-6. doi: 10.1007/s11605-008-0483-1. Epub 2008 Feb 7.
The aim of this study was to identify a preferable procedure reducing the incidence of delayed gastric emptying (DGE) after pylorus-preserving pancreatoduodenectomy (PPPD). Data on 132 consecutive patients with pancreatobiliary disease, who underwent PPPD, were collected retrospectively. A retrocolic Billroth I type reconstruction (B-I group) and an antecolic Roux-en Y type reconstruction (R-Y group) were performed for 54 and 78 patients after PPPD, respectively. Clinical measures of DGE were compared between the two groups. The incidence of DGE was 81% in B-I group and 10% in R-Y group (P < 0.001). The type of reconstruction (P < 0.001), operative time (P = 0.016), and postoperative complications (P = 0.001) were significantly associated with DGE by univariate analysis. Only the type of reconstruction (P < 0.001) was identified as an independent factor, which was associated with DGE by multivariate analysis. An antecolic Roux-en Y type duodenojejunostomy could be a useful reconstruction method after PPPD to prevent the occurrence of DGE.
本研究的目的是确定一种能降低保留幽门胰十二指肠切除术(PPPD)后胃排空延迟(DGE)发生率的更优手术方式。回顾性收集了132例连续接受PPPD的胰胆疾病患者的数据。PPPD术后分别对54例患者采用结肠后毕Ⅰ式重建(B-I组)和78例患者采用结肠前Roux-en-Y式重建(R-Y组)。比较两组DGE的临床指标。B-I组DGE发生率为81%,R-Y组为10%(P<0.001)。单因素分析显示,重建方式(P<0.001)、手术时间(P=0.016)和术后并发症(P=0.001)与DGE显著相关。多因素分析仅确定重建方式(P<0.001)为与DGE相关的独立因素。结肠前Roux-en-Y式十二指肠空肠吻合术可能是PPPD术后预防DGE发生的一种有用的重建方法。