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手掌和脚底出现紫色丘疹。

Violaceous papules on the palms and soles.

作者信息

Cheung-Lee Melody J, Rao Jaggi

机构信息

Division of Dermatology and Cutaneous Sciences, University of Alberta, Edmonton, AB, Canada.

出版信息

J Cutan Med Surg. 2008 Jan-Feb;12(1):35-7. doi: 10.2310/7750.2008.07024.

DOI:10.2310/7750.2008.07024
PMID:18258155
Abstract

BACKGROUND

Lichen planus (LP) is a condition with many clinical variants that can be quite varied in their presentation.

OBJECTIVE

We report a case of a 60-year-old woman who presented with a very unusual palmoplantar eruption characterized by violaceous pustule-like papules that was subsequently diagnosed as LP.

METHODS

The above case is reported, along with biopsy results. The patient was subsequently treated with a combination of topical corticosteroids and oral acitretin, and her clinical course was followed.

RESULTS

The eruption responded dramatically to our combination treatment and resolved by the 2-month follow-up.

CONCLUSION

Palmoplantar LP is a rare variant of LP that bears little resemblance to its classic LP. This condition responds well to a combination of potent topical corticosteroids and oral acitretin.

摘要

背景

扁平苔藓(LP)是一种具有多种临床变体的疾病,其表现形式差异很大。

目的

我们报告一例60岁女性病例,该患者出现了一种非常不寻常的掌跖皮疹,其特征为紫罗兰色脓疱样丘疹,随后被诊断为LP。

方法

报告上述病例及活检结果。该患者随后接受了外用糖皮质激素和口服阿维A的联合治疗,并对其临床病程进行了随访。

结果

皮疹对我们的联合治疗反应显著,在2个月的随访时消退。

结论

掌跖LP是LP的一种罕见变体,与经典LP几乎没有相似之处。这种情况对强效外用糖皮质激素和口服阿维A的联合治疗反应良好。

相似文献

1
Violaceous papules on the palms and soles.手掌和脚底出现紫色丘疹。
J Cutan Med Surg. 2008 Jan-Feb;12(1):35-7. doi: 10.2310/7750.2008.07024.
2
Palmoplantar lichen planus successfully treated with acitretin.阿维A成功治疗掌跖扁平苔藓。
BMJ Case Rep. 2015 Sep 7;2015:bcr2015211115. doi: 10.1136/bcr-2015-211115.
3
Coexistence of palmoplantar lichen planus and lupus erythematosus with response to treatment using acitretin.掌跖扁平苔藓与红斑狼疮并存及阿维A治疗反应
Br J Dermatol. 1996 Mar;134(3):538-41.
4
Lichen planus with palmoplantar involvement: rapid therapeutic response to acitretin.伴有掌跖受累的扁平苔藓:对阿维A的快速治疗反应
Eur J Dermatol. 2011 Jul-Aug;21(4):632-3. doi: 10.1684/ejd.2011.1453.
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Palmoplantar lichen planus presenting with vesicle-like papules.表现为水疱样丘疹的掌跖扁平苔藓。
J Dermatol. 2003 Apr;30(4):337-40. doi: 10.1111/j.1346-8138.2003.tb00397.x.
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Disseminated hypertrophic lichen planus: relevant response to acitretin.播散性肥厚性扁平苔藓:对阿维A的相关反应
An Bras Dermatol. 2011 Jul-Aug;86(4 Suppl 1):S96-9. doi: 10.1590/s0365-05962011000700025.
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Cutaneous ulcerative lichen planus exhibiting pathergy, response to acitretin.表现为同形反应的皮肤溃疡性扁平苔藓,对阿维A的反应
J Drugs Dermatol. 2004 Mar-Apr;3(2):191-2.
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Lupus erythematosus/lichen planus overlap syndrome: successful treatment with acitretin.红斑狼疮/扁平苔藓重叠综合征:阿维 A 酯治疗获得成功。
Lupus. 2013 Jul;22(8):851-4. doi: 10.1177/0961203313492243. Epub 2013 Jun 11.
9
[Treatment of lichen planus pemphigoides with acitretin and pulsed corticosteroids].阿维A与脉冲式皮质类固醇治疗类天疱疮样扁平苔藓
Hautarzt. 2003 Mar;54(3):268-73. doi: 10.1007/s00105-002-0394-0. Epub 2003 Jan 11.
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Acitretin for the management of generalized cutaneous lichen planus.阿维A用于泛发性皮肤扁平苔藓的治疗。
Dermatol Online J. 2014 Sep 16;20(9):13030/qt2m36z4jm.

引用本文的文献

1
Treatment modalities of palmoplantar lichen planus: a brief review.掌跖扁平苔藓的治疗方式:简要综述
Postepy Dermatol Alergol. 2016 Dec;33(6):411-415. doi: 10.5114/ada.2016.63879. Epub 2016 Dec 2.
2
Palmoplantar lichen planus successfully treated with acitretin.阿维A成功治疗掌跖扁平苔藓。
BMJ Case Rep. 2015 Sep 7;2015:bcr2015211115. doi: 10.1136/bcr-2015-211115.
3
Predominant palmoplantar lichen planus: a diagnostic challenge.掌跖部扁平苔藓为主型:一项诊断挑战。
Indian J Dermatol. 2014 Jul;59(4):343-7. doi: 10.4103/0019-5154.135477.