Feily Amir, Yaghoobi Reza, Nilforoushzadeh Mohammad Ali
Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Jundishapur University of Medical Science, Ahvaz, Iran.
Postepy Dermatol Alergol. 2016 Dec;33(6):411-415. doi: 10.5114/ada.2016.63879. Epub 2016 Dec 2.
Palmoplantar lichen planus is a localized and uncommon variant of lichen planus which is mostly resistant to treatment. Our purpose was to discuss all treatment modalities proposed and tested for palmoplantar lichen planus in the literature. A systematic review of the literature was conducted to evaluate evidence regarding all treatment modalities proposed and tested for palmoplantar lichen planus in the literature. Two major databases (PubMed, Google scholar) were searched. The review included all case reports, letters and original articles reporting any treatment for palmoplantar lichen planus but not treatment used in the other type of lichen planus, generalized lichen planus or other type of palmoplantar dermatoses. We have gone over more than 50 articles. There are many drugs that have been used in the treatment of lichen planus and generalized lichen planus but the palmoplantar type is a rare variety of lichen planus. That is why we could not find any clinical trial on the subject and just case reports have been described in this manuscript. In spite of plentiful investigations carried out on lichen planus, there is no treatment modality that has proved to be utterly satisfactory in treatment of palmoplantar lichen planus.
掌跖扁平苔藓是扁平苔藓的一种局限性且不常见的变体，大多对治疗有抵抗性。我们的目的是讨论文献中提出并测试过的用于治疗掌跖扁平苔藓的所有治疗方式。我们对文献进行了系统回顾，以评估有关文献中提出并测试过的用于治疗掌跖扁平苔藓的所有治疗方式的证据。我们检索了两个主要数据库（PubMed、谷歌学术）。该综述纳入了所有报告对掌跖扁平苔藓进行任何治疗的病例报告、信函和原创文章，但不包括用于其他类型扁平苔藓（泛发性扁平苔藓）或其他类型掌跖皮肤病的治疗方法。我们查阅了50多篇文章。有许多药物已用于治疗扁平苔藓和泛发性扁平苔藓，但掌跖型是扁平苔藓的一种罕见类型。这就是为什么我们在该主题上找不到任何临床试验，且本手稿中仅描述了病例报告。尽管对扁平苔藓进行了大量研究，但在治疗掌跖扁平苔藓方面，尚无已被证明完全令人满意的治疗方式。
