Youssef Nader N, Atienza Katherine, Langseder Annette L, Strauss Richard S
Center for Pediatric Irritable Bowel & Motility Disorders, Goryeb Childrens Hospital at Atlantic Health, Morristown, New Jersey, USA.
Clin Gastroenterol Hepatol. 2008 Mar;6(3):329-32. doi: 10.1016/j.cgh.2007.12.019. Epub 2008 Feb 7.
BACKGROUND & AIMS: Abdominal pain is common in adolescence. The aim of this study was to determine the prevalence of depressive symptoms in a large cohort of patients with frequent abdominal pain.
A prospective, cross-sectional, nationally representative sample of children aged 13 to 18 years (mean age, 16.2 +/- 1.7 y; 49% male) completed in-home interviews and separate in-school questionnaires for the National Longitudinal Study in Adolescent Health (the Add Health Study). Depressed mood was assessed with the Center for Epidemiologic Studies Depression Scale. Subjective measures of abdominal pain were reported by 20,745 adolescents from wave 1 of the Add Health Study. Frequency of abdominal pain over the previous 1 year was rated as rare (0-1 episode/wk), moderate (2-3 episodes/wk), or daily (>or=4 episodes/wk).
Daily pain is reported in 3.2% of adolescents, with an additional 14% reporting pain as moderate in frequency. Sixteen percent of all adolescents are at risk for developing depression. The risk for depression goes from 16% to 45% (P < .001) when the pain is daily. Compared with rare pain, children with daily pain were more likely to miss school 10 or more times per year (46% vs 19%, P < .001), cry (12.1% vs 1%, P < .001), feel sad (25.2% vs 5.3%, P < .001), and lonely (25.2% vs 6.4%, P < .001). Children with daily pain were likely to consider life a failure versus those with no pain (10.2% vs 3.3%, P < .001).
Adolescents with frequent abdominal pain are at increased risk for depressive symptoms, social isolation, and missing school.
腹痛在青少年中很常见。本研究的目的是确定一大群频繁腹痛患者中抑郁症状的患病率。
一项前瞻性、横断面、具有全国代表性的研究，选取了13至18岁的儿童（平均年龄16.2±1.7岁；49%为男性），他们完成了家庭访谈以及针对青少年健康全国纵向研究（“青少年健康研究”）的校内单独问卷调查。使用流行病学研究中心抑郁量表评估抑郁情绪。“青少年健康研究”第一波的20745名青少年报告了腹痛的主观测量结果。将过去1年中腹痛的频率评定为罕见（0 - 1次/周）、中度（2 - 3次/周）或每日（≥4次/周）。
3.2%的青少年报告每日腹痛，另有14%报告腹痛频率为中度。所有青少年中有16%有患抑郁症的风险。当腹痛为每日发作时，患抑郁症的风险从16%升至45%（P < .001）。与罕见腹痛相比，每日腹痛的儿童每年缺课10次或更多次的可能性更大（46%对19%，P < .001），哭泣的可能性更大（12.1%对1%，P < .001），感到悲伤的可能性更大（25.2%对5.3%，P < .001），感到孤独的可能性更大（25.2%对6.4%，P < .001）。与无腹痛的儿童相比，每日腹痛的儿童更有可能认为生活是失败的（10.2%对3.3%，P < .001）。
频繁腹痛的青少年出现抑郁症状、社交孤立和缺课的风险增加。
