Vardar Selma Arzu, Oztürk Levent, Altun Armağan, Turan Nesrin
Department of Physiology, Faculty of Medicine, Trakya University, Edirne, Turkey.
Anadolu Kardiyol Derg. 2008 Feb;8(1):27-31.
The effects of body mass index (BMI) on ventricular repolarization in young men have not been studied in detail. The QT and JT intervals are measured to estimate the duration of the ventricular repolarization. As new repolarization parameters, the time intervals between the J point to the apex of the T wave (JTa), the apex and the end of T wave (TaTe) may be associated with arrhythmogenesis in clinical conditions. The aim of this study was to compare ventricular repolarization parameters in overweight and normal weight healthy young men.
Thirty-six overweight men (BMI--26.3+/-1.5 kg/m2, mean age--20.6+/-1.5 years) and 149 men within normal limits (BMI--21.9+/-1.5 kg/m2, mean age--20.4+/-1.4 yrs) were included in this cross-sectional controlled study. The body mass index of 25 to 29.9 kg/m2 was defined as overweight and scores of 18.5 to 24.9 kg/m2 were accepted as normal. Ventricular repolarization parameters including QT, JT, JTa, TaTe, RR intervals duration and heart rate-corrected values of QT (QTc), JT (JTc), JTa (JTac), and TaTe (TaTec) intervals duration were obtained from lead V2 and considered to be representative of the ventricular repolarization process.
We found similar ventricular repolarization parameters (QT, JT, JTa, TaTe, RR, QTc, JTc, JTac, and TaTec) in overweight and normal groups. Uncorrected and corrected ventricular repolarization parameters were not correlated with BMI.
Ventricular repolarization features in young men who are overweight in terms of BMI seem to show no significant difference when compared to normal weight men.
体重指数(BMI)对年轻男性心室复极的影响尚未得到详细研究。测量QT和JT间期以估计心室复极的持续时间。作为新的复极参数,J点至T波顶点(JTa)、T波顶点与终点(TaTe)之间的时间间隔可能与临床情况下的心律失常发生有关。本研究的目的是比较超重和正常体重健康年轻男性的心室复极参数。
本横断面对照研究纳入了36名超重男性(BMI——26.3±1.5kg/m²,平均年龄——20.6±1.5岁)和149名体重正常男性(BMI——21.9±1.5kg/m²,平均年龄——20.4±1.4岁)。体重指数在25至29.9kg/m²之间定义为超重,18.5至24.9kg/m²之间视为正常。从V2导联获得包括QT、JT、JTa、TaTe、RR间期持续时间以及QT(QTc)、JT(JTc)、JTa(JTac)和TaTe(TaTec)间期持续时间的心率校正值等心室复极参数,并认为这些参数代表心室复极过程。
我们发现超重组和正常组的心室复极参数(QT、JT、JTa、TaTe、RR、QTc、JTc、JTac和TaTec)相似。未校正和校正后的心室复极参数与BMI均无相关性。
就BMI而言超重的年轻男性,其心室复极特征与正常体重男性相比似乎无显著差异。