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1
Strategies for prescribing statins.他汀类药物的处方策略。
BMJ. 2008 Feb 9;336(7639):288-9. doi: 10.1136/bmj.39387.573947.80.
2
[Statins: for the time being, do not as a rule prescribe the maximum dose].他汀类药物：目前，通常不要开具最大剂量。
Ned Tijdschr Geneeskd. 2005 Nov 12;149(46):2589; author reply 2589-90.
3
Suboptimal use of statins at treatment initiation.
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Discontinuation of Statins at the End of Life #322.临终时停用他汀类药物#322
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Statins: the case for higher, individualized starting doses.
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6
Which statin, what dose?哪种他汀类药物，多大剂量？
Drug Ther Bull. 2007 May;45(5):33-7. doi: 10.1136/dtb.2007.45533.
7
Prescribing statins to patients with nonalcoholic fatty liver disease: real cardiovascular benefits outweigh theoretical hepatotoxic risk.给非酒精性脂肪性肝病患者开具他汀类药物：实际心血管益处超过理论上的肝毒性风险。
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Treatment with statins in high-risk patients: relevance of time to titration of dose and adverse outcomes.高危患者使用他汀类药物治疗：剂量滴定时间与不良结局的相关性
Am J Cardiovasc Drugs. 2009;9(3):211-2; author reply 212. doi: 10.2165/00129784-200909030-00007.

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3
A cluster randomised controlled trial of a pharmacist-led collaborative intervention to improve statin prescribing and attainment of cholesterol targets in primary care.一项由药剂师主导的协作干预措施的整群随机对照试验，旨在改善初级保健中他汀类药物的处方开具情况及胆固醇目标的达成情况。
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Strategies for statins: The CASE for fire and forget.他汀类药物的策略：一劳永逸的情况。
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Strategies for statins: Treat to target benefits no one.他汀类药物治疗策略：“治疗至靶点”对任何人都没有益处。
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本文引用的文献

1
Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: a meta-analysis.他汀类药物14项随机试验中18686例糖尿病患者降脂治疗的疗效：一项荟萃分析。
Lancet. 2008 Jan 12;371(9607):117-25. doi: 10.1016/S0140-6736(08)60104-X.
2
Should we lower cholesterol as much as possible?我们应该尽可能降低胆固醇水平吗？
BMJ. 2006 Jun 3;332(7553):1330-2. doi: 10.1136/bmj.332.7553.1330.
3
Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins.降低胆固醇治疗的疗效与安全性：对他汀类药物14项随机试验中90,056名参与者数据的前瞻性荟萃分析
Lancet. 2005 Oct 8;366(9493):1267-78. doi: 10.1016/S0140-6736(05)67394-1. Epub 2005 Sep 27.
4
Intensive lipid lowering with atorvastatin in patients with stable coronary disease.阿托伐他汀强化降脂治疗稳定型冠心病患者
N Engl J Med. 2005 Apr 7;352(14):1425-35. doi: 10.1056/NEJMoa050461. Epub 2005 Mar 8.
5
Treatment with drugs to lower blood pressure and blood cholesterol based on an individual's absolute cardiovascular risk.根据个体的绝对心血管风险，使用药物降低血压和血液胆固醇。
Lancet. 2005;365(9457):434-41. doi: 10.1016/S0140-6736(05)17833-7.
6
Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report.美国国家胆固醇教育计划（NCEP）成人高血胆固醇检测、评估与治疗专家小组第三次报告（成人治疗小组第三次报告）最终报告。
Circulation. 2002 Dec 17;106(25):3143-421.
7
MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial.辛伐他汀降低胆固醇对20536例高危个体的MRC/BHF心脏保护研究：一项随机安慰剂对照试验。
Lancet. 2002 Jul 6;360(9326):7-22. doi: 10.1016/S0140-6736(02)09327-3.
8
Resource management in prevention of coronary heart disease: optimising prescription of lipid-lowering drugs.冠心病预防中的资源管理：优化降脂药物处方
Lancet. 2002 Jun 29;359(9325):2271-3. doi: 10.1016/S0140-6736(02)09299-1.
9
Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III).国家胆固醇教育计划（NCEP）成人高血胆固醇检测、评估与治疗专家小组第三次报告（成人治疗小组第三次报告）执行摘要
JAMA. 2001 May 16;285(19):2486-97. doi: 10.1001/jama.285.19.2486.
10
The lipid treatment assessment project (L-TAP): a multicenter survey to evaluate the percentages of dyslipidemic patients receiving lipid-lowering therapy and achieving low-density lipoprotein cholesterol goals.脂质治疗评估项目（L-TAP）：一项多中心调查，旨在评估接受降脂治疗并达到低密度脂蛋白胆固醇目标的血脂异常患者的百分比。
Arch Intern Med. 2000 Feb 28;160(4):459-67. doi: 10.1001/archinte.160.4.459.

他汀类药物的处方策略。

Strategies for prescribing statins.

作者信息

Donner-Banzhoff Norbert, Sönnichsen Andreas

出版信息

BMJ. 2008 Feb 9;336(7639):288-9. doi: 10.1136/bmj.39387.573947.80.

DOI:10.1136/bmj.39387.573947.80
PMID:18258935
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2234555/
Abstract

Evidence supports prescribing a standard dose without further testing or dose adjustment

摘要

有证据支持在不进行进一步检测或剂量调整的情况下开具标准剂量的处方。