Bilo H J, Gans R O, Polee M B, van der Maten J, Popp-Snijders C, Donker A J
Department of Internal Medicine, Free University Hospital, Amsterdam, The Netherlands.
Diabet Med. 1991;8 Spec No:S108-12. doi: 10.1111/j.1464-5491.1991.tb02169.x.
To evaluate the influence of blood glucose control on serum catecholamine levels (which reflect both plasma and platelet levels), six healthy non-diabetic subjects, seven well-controlled Type 1 diabetic patients, and six poorly controlled Type 1 diabetic patients were studied before (baseline) and after standardized exercise. A significant correlation was found between serum noradrenaline and HbA1 at baseline (r = 0.53, p less than 0.025) and after exercise (r = 0.71, p less than 0.001). Similar results were found for serum adrenaline (r = 0.68, p less than 0.005 and r = 0.61, p less than 0.005, respectively) and consequently total serum catecholamine content (r = 0.65, p less than 0.005 and r = 0.75, p less than 0.001, respectively). However, no relationship was found between serum catecholamine levels and actual blood glucose levels, age, body mass index or insulin dose. A moderate correlation was found between systolic blood pressure and serum levels of noradrenaline and total catecholamines after exercise (r = 0.48 and r = 0.48, both p less than 0.025).
为评估血糖控制对血清儿茶酚胺水平（反映血浆和血小板水平）的影响，对6名健康非糖尿病受试者、7名血糖控制良好的1型糖尿病患者和6名血糖控制不佳的1型糖尿病患者在标准化运动前（基线）和运动后进行了研究。在基线时（r = 0.53，p < 0.025）和运动后（r = 0.71，p < 0.001），血清去甲肾上腺素与糖化血红蛋白之间存在显著相关性。血清肾上腺素也得到了类似结果（分别为r = 0.68，p < 0.005和r = 0.61，p < 0.005），因此血清总儿茶酚胺含量也有类似结果（分别为r = 0.65，p < 0.005和r = 0.75，p < 0.001）。然而，未发现血清儿茶酚胺水平与实际血糖水平、年龄、体重指数或胰岛素剂量之间存在关联。运动后收缩压与血清去甲肾上腺素水平和总儿茶酚胺水平之间存在中度相关性（r = 0.48和r = 0.48，p均< 0.025）。
