Garfin S R, Rydevik B L, Brown R A
Division of Orthopaedics and Rehabilitation, University of California, San Diego.
Spine (Phila Pa 1976). 1991 Feb;16(2):162-6.
Pathophysiologically, nerve root pain production is a complex issue. For many years, mechanical compression has been regarded as the sole cause for such pain. There are indications, however, that other factors, such as intraneural inflammation, may be of importance in this context. In this article, four cases are presented in which nerve root related pain gradually resolved without any proven change in the mechanical deformation of the involved nerve root. The data presented here suggest that mechanical compression, per se, may not always be the sole cause of radicular pain and dysfunction. These findings suggest that improvement is needed in our understanding of the pathophysiology of nerve root compression and inflammation.
在病理生理学上，神经根性疼痛的产生是一个复杂的问题。多年来，机械性压迫一直被视为此类疼痛的唯一原因。然而，有迹象表明，其他因素，如神经内炎症，在这种情况下可能也很重要。在本文中，我们呈现了四个病例，其中与神经根相关的疼痛逐渐缓解，而受累神经根的机械变形并未有任何经证实的改变。此处呈现的数据表明，机械性压迫本身可能并不总是神经根性疼痛和功能障碍的唯一原因。这些发现表明，我们需要改进对神经根压迫和炎症病理生理学的理解。
