Beigi R, Hanrahan J
Department of Obstetrics, Gynecology & Reproductive Sciences, Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Infect Dis Obstet Gynecol. 2007;2007:70876. doi: 10.1155/2007/70876.
To determine colonization rates of Staphylococcus aureus given the potential for future intervention trials aimed at reducing surgical-site infectious morbidity, and to estimate methicillin-resistant Staphylococcus aureus (MRSA) rates in our patient population.
Prospective pilot investigation comprising data from 104 gravidas admitted to an urban labor and delivery unit. All underwent anterior nares culture collection with a subset also undergoing vaginal culture collection.
Twenty-two percent of women were colonized in the anterior nares. Of the 28 women who had vaginal cultures collected, 4/28 (14.2%) demonstrated Staphylococcus aureus colonization. There was 82% concordance between the nares and vagina. Nine percent of isolates were MRSA strains. Overall, 2/96 (2.1%) of women were MRSA-colonized.
Rates of Staphylococcus aureus colonization among gravidas entering labor and delivery are modest and consistent with the general population. MRSA rates among gravidas appear to be reassuringly low in this pilot study.
鉴于未来有开展旨在降低手术部位感染发病率的干预试验的可能性，确定金黄色葡萄球菌的定植率，并估算我们患者群体中耐甲氧西林金黄色葡萄球菌（MRSA）的比率。
前瞻性试点调查，纳入了104名入住城市产科病房的孕妇的数据。所有孕妇均接受了前鼻孔培养物采集，其中一部分还接受了阴道培养物采集。
22%的女性在前鼻孔定植。在28名接受阴道培养的女性中，4/28（14.2%）显示有金黄色葡萄球菌定植。鼻孔和阴道之间的一致性为82%。9%的分离株为MRSA菌株。总体而言，2/96（2.1%）的女性为MRSA定植。
进入分娩期的孕妇中金黄色葡萄球菌定植率适中，与普通人群一致。在这项试点研究中，孕妇中的MRSA比率似乎低得令人安心。
