• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

将布林利图用于新用途：对老年人功能性脑成像数据的荟萃分析。

Resurrecting brinley plots for a novel use: meta-analyses of functional brain imaging data in older adults.

作者信息

Peiffer Ann M, Maldjian Joseph A, Laurienti Paul J

机构信息

Department of Radiology, Wake Forest University School of Medicine, Medical Center Boulevard, PP1 - 7th Floor, Winston-Salem, NC 27157, USA.

出版信息

Int J Biomed Imaging. 2008;2008:167078. doi: 10.1155/2008/167078.

DOI:10.1155/2008/167078
PMID:18274664
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2233772/
Abstract

By plotting response times of young and older adults across a variety of tasks, Brinley spurred investigation and debate into the theory of general cognitive slowing. Though controversial, Brinley plots can assess between-task differences, the impact of increasing task demand, and the relationship between responses in two groups of subjects. Since a relationship exists between response times and the blood-oxygen level dependent (BOLD) signal of functional MRI (fMRI), Brinley's plotting method could be applied as a meta-analysis tool in fMRI studies of aging. Here, fledgling "Peiffer plots" are discussed for their potential impact on understanding general cognitive brain activity in aging. Preliminary results suggest that general cognitive slowing may be localized at the sensorimotor transformation in the precentral gyrus. Although this meta-analysis method is naturally used with imaging studies of aging, theoretically it may be applied to other study pairs (e.g., schizophrenic versus normal) or imaging datasets (e.g., PET).

摘要

通过绘制年轻人和老年人在各种任务中的反应时间，布林利激发了对一般认知减缓理论的研究和辩论。尽管存在争议，但布林利图可以评估任务间差异、任务需求增加的影响以及两组受试者反应之间的关系。由于反应时间与功能磁共振成像（fMRI）的血氧水平依赖（BOLD）信号之间存在关联，布林利的绘图方法可作为衰老的fMRI研究中的一种元分析工具。在此，将讨论新兴的“派弗图”对理解衰老过程中一般认知脑活动的潜在影响。初步结果表明，一般认知减缓可能定位于中央前回的感觉运动转换区。虽然这种元分析方法自然适用于衰老的影像学研究，但理论上它也可应用于其他研究对（如精神分裂症患者与正常人）或成像数据集（如正电子发射断层扫描）。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09f/2233772/01490e94a460/IJBI2008-167078.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09f/2233772/b6856769dfdf/IJBI2008-167078.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09f/2233772/87ae6da89bda/IJBI2008-167078.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09f/2233772/9bb2ab2a016b/IJBI2008-167078.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09f/2233772/9c4eef28190b/IJBI2008-167078.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09f/2233772/bc8f1f20d256/IJBI2008-167078.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09f/2233772/01490e94a460/IJBI2008-167078.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09f/2233772/b6856769dfdf/IJBI2008-167078.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09f/2233772/87ae6da89bda/IJBI2008-167078.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09f/2233772/9bb2ab2a016b/IJBI2008-167078.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09f/2233772/9c4eef28190b/IJBI2008-167078.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09f/2233772/bc8f1f20d256/IJBI2008-167078.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c09f/2233772/01490e94a460/IJBI2008-167078.006.jpg

相似文献

1
Resurrecting brinley plots for a novel use: meta-analyses of functional brain imaging data in older adults.将布林利图用于新用途：对老年人功能性脑成像数据的荟萃分析。
Int J Biomed Imaging. 2008;2008:167078. doi: 10.1155/2008/167078.
2
What Can Brinley Plots Tell Us About Cognitive Aging? Exploring Simulated Data and Modified Brinley Plots.布林利图能告诉我们关于认知衰老的哪些信息？探索模拟数据和修正后的布林利图。
Front Psychol. 2022 Feb 18;13:797583. doi: 10.3389/fpsyg.2022.797583. eCollection 2022.
3
Combining movement kinematics, efficiency functions, and Brinley plots to study age-related slowing of sensorimotor processes: insights from Fitts' task.结合运动运动学、效率函数和布林利图研究与年龄相关的感觉运动过程的减缓：来自 Fitts 任务的见解。
Gerontology. 2012;58(2):171-80. doi: 10.1159/000329347. Epub 2011 Jul 20.
4
Explicitly modeling the effects of aging on response time.明确模拟衰老对反应时间的影响。
Psychon Bull Rev. 2000 Mar;7(1):1-25. doi: 10.3758/bf03210723.
5
Brinley plots, explained variance, and the analysis of age differences in response latencies.布林利图、解释方差以及反应潜伏期年龄差异分析。
J Gerontol. 1994 Mar;49(2):P72-80. doi: 10.1093/geronj/49.2.p72.
6
Brinley plots and theories of aging: the explicit, muddled, and implicit debates.布林利图表与衰老理论：明确的、混乱的和隐含的争论。
J Gerontol. 1994 Mar;49(2):P81-9. doi: 10.1093/geronj/49.2.p81.
7
What can Brinley plots tell us about cognitive aging?布林利图能告诉我们关于认知衰老的哪些信息？
J Gerontol. 1994 Mar;49(2):P60-4. doi: 10.1093/geronj/49.2.p60.
8
Analysis of group differences in processing speed: Brinley plots, Q-Q plots, and other conspiracies.处理速度的组间差异分析：布林利图、Q-Q图及其他相关内容
Psychon Bull Rev. 2003 Mar;10(1):224-37. doi: 10.3758/bf03196489.
9
The effects of aging on reaction time in a signal detection task.衰老对信号检测任务中反应时间的影响。
Psychol Aging. 2001 Jun;16(2):323-41.
10
Reaction time slowing in adults with HIV: results of a meta-analysis using brinley plots.感染HIV的成年人反应时间减慢：使用布林利图的荟萃分析结果
Brain Cogn. 2002 Oct;50(1):25-34. doi: 10.1016/s0278-2626(02)00007-6.

引用本文的文献

1
Is evidence-based treatment helping my patient? Utilizing modified Brinley plots to measure clinical change.基于证据的治疗是否对我的患者有帮助？利用改良的布林利图来衡量临床变化。
Clin Psychol (New York). 2019 Mar;26(1). doi: 10.1111/cpsp.12272. Epub 2018 Dec 28.

本文引用的文献

1
Aging and the interaction of sensory cortical function and structure.衰老以及感觉皮层功能与结构的相互作用。
Hum Brain Mapp. 2009 Jan;30(1):228-40. doi: 10.1002/hbm.20497.
2
Motor-response generation as a source of aging-related behavioural slowing in choice-reaction tasks.在选择反应任务中，运动反应生成作为与衰老相关的行为迟缓的一个根源。
Neurobiol Aging. 2006 Nov;27(11):1719-30. doi: 10.1016/j.neurobiolaging.2005.09.027. Epub 2005 Oct 24.
3
Neuroimaging studies of practice-related change: fMRI and meta-analytic evidence of a domain-general control network for learning.
与练习相关变化的神经影像学研究：功能磁共振成像及学习领域通用控制网络的元分析证据
Brain Res Cogn Brain Res. 2005 Dec;25(3):607-23. doi: 10.1016/j.cogbrainres.2005.08.013. Epub 2005 Oct 20.
4
Involvement of the inferior frontal junction in cognitive control: meta-analyses of switching and Stroop studies.额下回交界处参与认知控制：转换和斯特鲁普研究的荟萃分析。
Hum Brain Mapp. 2005 May;25(1):22-34. doi: 10.1002/hbm.20127.
5
Meta-analysis of functional imaging data using replicator dynamics.使用复制动态对功能成像数据进行荟萃分析。
Hum Brain Mapp. 2005 May;25(1):165-73. doi: 10.1002/hbm.20133.
6
Neuroimaging studies of shifting attention: a meta-analysis.注意力转移的神经影像学研究：一项荟萃分析。
Neuroimage. 2004 Aug;22(4):1679-93. doi: 10.1016/j.neuroimage.2004.03.052.
7
Assessing the auditory dual-pathway model in humans.评估人类听觉双通路模型。
Neuroimage. 2004 May;22(1):401-8. doi: 10.1016/j.neuroimage.2004.01.014.
8
Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRI.默认模式网络活动可区分阿尔茨海默病与健康衰老：来自功能磁共振成像的证据。
Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4637-42. doi: 10.1073/pnas.0308627101. Epub 2004 Mar 15.
9
Task-independent and task-specific age effects on brain activity during working memory, visual attention and episodic retrieval.在工作记忆、视觉注意力和情景记忆检索过程中，与任务无关和特定于任务的年龄对大脑活动的影响。
Cereb Cortex. 2004 Apr;14(4):364-75. doi: 10.1093/cercor/bhg133.
10
Sensorimotor slowing with ageing is mediated by a functional dysregulation of motor-generation processes: evidence from high-resolution event-related potentials.衰老导致的感觉运动减慢是由运动产生过程的功能失调介导的：来自高分辨率事件相关电位的证据。
Brain. 2004 Feb;127(Pt 2):351-62. doi: 10.1093/brain/awh042. Epub 2003 Nov 7.