Hardy David J, Hinkin Charles H
University of California, Los Angeles, CA, USA.
Brain Cogn. 2002 Oct;50(1):25-34. doi: 10.1016/s0278-2626(02)00007-6.
A meta-analysis in the form of Brinley plots was conducted on the mean reaction times of HIV+ and HIV- groups. HIV+ reaction times were regressed on HIV- reaction times across 122 task conditions from 29 studies, producing a highly linear function (r(2) = .94), with a slope b = 1.039, which was not significantly different than b = 1.00. Asymptomatic and symptomatic HIV+ reaction times were also separately regressed on HIV- reaction times across 67 task conditions from 13 studies. Both functions were highly linear (r(2) = .97 and.90 respectively), with slopes of 1.034 and 1.117 respectively. Only the slope for symptomatic HIV+ groups was significantly larger than b = 1.00, suggesting a modest generalized slowing of cognition in these adults.
采用布林利图的形式对HIV阳性和HIV阴性组的平均反应时间进行了荟萃分析。在来自29项研究的122种任务条件下，将HIV阳性组的反应时间与HIV阴性组的反应时间进行回归分析，得出一个高度线性的函数（r² = 0.94），斜率b = 1.039，与b = 1.00没有显著差异。在来自13项研究的67种任务条件下，还分别将无症状和有症状HIV阳性组的反应时间与HIV阴性组的反应时间进行回归分析。两个函数均高度线性（r²分别为0.97和0.90），斜率分别为1.034和1.117。只有有症状HIV阳性组的斜率显著大于b = 1.00，这表明这些成年人的认知存在适度的普遍减慢。
