Pangonyte Dalia, Stalioraityte Elena, Kazlauskaite Danute, Ziuraitiene Reda, Stanioniene Zita, Kerpauskiene Sonata
Laboratory of Cardiac Pathology, Institute of Cardiology, Kaunas University of Medicine, Kaunas, Lithuania.
Medicina (Kaunas). 2008;44(1):8-14.
The aim of the study was to determine ventricular and atrial cardiometric parameters at preinfarction and postinfarction stage of ischemic heart disease.
Cardiometric parameters (mass, endocardial surface area, the tracts of flow and outflow, etc.) of 132 men (mean age of 49.7+/-8.9 years) who had died suddenly during prehospital period (within 6 hours) after the first or repeated acute event of "pure" ischemic heart disease were investigated. These patients had no other, except ischemia, factors predisposing myocardial hypertrophy as well as clinical symptoms of heart failure. The decedents were divided into preinfarction (71 men) and postinfarction ischemic heart disease (61 men) groups.
At preinfarction stage of ischemic heart disease, mass and endocardial surface area of all parts of the heart were increased, the tracts of flow and outflow--longer. At postinfarction stage, only corresponding left ventricular and atrial parameters were more increased.
Eccentric type of left ventricular hypertrophy (proportional increase of mass and endocardial surface area) and concentric type of right ventricular and right and left atrial hypertrophy (the part of myocardium mass per unit of endocardial area is greater) were determined at preinfarction stage of ischemic heart disease. At postinfarction stage, at least as far as evidence of heart failure is not overt, only the corresponding left ventricular and atrial hypertrophy progresses.
本研究旨在确定缺血性心脏病梗死前和梗死后阶段的心室和心房心脏测量参数。
对132名男性（平均年龄49.7±8.9岁）进行了研究，这些男性在首次或反复发生“单纯”缺血性心脏病急性事件后，于院前阶段（6小时内）突然死亡。除缺血外，这些患者没有其他易导致心肌肥厚的因素以及心力衰竭的临床症状。死者被分为梗死前（71名男性）和梗死后缺血性心脏病（61名男性）两组。
在缺血性心脏病梗死前阶段，心脏各部位的质量和心内膜表面积增加，血流和流出道延长。在梗死后阶段，只有相应的左心室和心房参数增加得更多。
在缺血性心脏病梗死前阶段，确定为左心室肥厚的离心型（质量和心内膜表面积成比例增加）以及右心室和右心房及左心房肥厚的向心型（单位心内膜面积的心肌质量部分更大）。在梗死后阶段，至少在没有明显心力衰竭证据的情况下，只有相应的左心室和心房肥厚会进展。
