Augustaitytė Agnė, Kalinauskienė Eglė
Faculty of Medicine, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Hospital of the Lithuanian University of Health Sciences Kauno klinikos, Kaunas, Lithuania.
Acta Med Litu. 2022;29(1):91-99. doi: 10.15388/Amed.2021.29.1.12. Epub 2022 Jul 26.
Left ventricular hypertrophy (LVH) regardless of other risk factors may be associated with an increased risk of mortality from cardiovascular diseases. Therefore, timely diagnosis for LVH is important in order to avoid possible complications. One of the simplest and cheapest methods to diagnose LVH is electrocardiography (ECG). Although a number of ECG criteria for LVH is known, their reliability varies in many studies.
To evaluate the reliability of ECG criteria for LVH based on transthoracic echocardiography (TTE) data.
The study included all consecutive patients in Kaunas Clinical Hospital Department of Cardiology from December 2019 until March 2020 and from September until October 2020, after applying the inclusion and exclusion criteria. The sensitivity and specificity of the ECG criteria for LVH were assessed based on TTE measurements performed during the same inpatient setting. The reliability of the ECG criteria for LVH was assessed using ROC curves. Reliability differences in gender, age and nutritional status groups were assessed using ANOVA statistical method.
Data from 95 patients were analyzed (63.2% were women and 36.8% were men). The sensitivity, specificity and AUC of Sokolow-Lyon criterion were 9.38%, 85.71% and 0.44 (p = 0.034), R in aVL - 6.25%, 90.48% and 0.51 (p = 0.038), Cornell - 21.88%, 100 % and0.69 (p = 0.084), Cornell product - 31.25%, 95.24% and 0.72 (p = 0.070), Peguero-Lo Presti - 31.25%, 85.71% and 0.68 (p = 0.053), respectively. No statistically significant differences were observed among the individual gender, age and nutritional status groups.
Sokolow-Lyon and RaVL criteria were not statistically significantly reliable in LVH diagnosis compared to TTE, unlike the Cornell, Cornell product, and Peguero-Lo Presti criteria.
无论其他风险因素如何,左心室肥厚(LVH)可能与心血管疾病死亡率增加相关。因此,及时诊断LVH对于避免可能的并发症很重要。诊断LVH最简单且最便宜的方法之一是心电图(ECG)。尽管已知许多LVH的ECG标准,但在许多研究中它们的可靠性各不相同。
基于经胸超声心动图(TTE)数据评估LVH的ECG标准的可靠性。
在应用纳入和排除标准后,该研究纳入了2019年12月至2020年3月以及2020年9月至10月考纳斯临床医院心脏病科的所有连续患者。基于在同一住院期间进行的TTE测量评估LVH的ECG标准的敏感性和特异性。使用ROC曲线评估LVH的ECG标准的可靠性。使用方差分析统计方法评估性别、年龄和营养状况组之间的可靠性差异。
分析了95例患者的数据(63.2%为女性,36.8%为男性)。索科洛夫-里昂标准的敏感性、特异性和AUC分别为9.38%、85.71%和0.44(p = 0.034),aVL导联R波标准为6.25%、90.48%和0.51(p = 0.038),康奈尔标准为21.88%、100%和0.69(p = 0.084),康奈尔乘积标准为31.25%、95.24%和0.72(p = 0.070),佩格罗-洛普雷斯蒂标准为31.25%、85.71%和0.68(p = 0.053)。在各个性别、年龄和营养状况组之间未观察到统计学上的显著差异。
与TTE相比,索科洛夫-里昂和aVL导联R波标准在LVH诊断中统计学上可靠性不显著,而康奈尔、康奈尔乘积和佩格罗-洛普雷斯蒂标准则不然。