Holzer Brigitte, Rosen Harald R, Zaglmaier Wolfgang, Klug Reinhold, Beer Bernhard, Novi Gabriele, Schiessel Rudolf
Surgical Department, Danube Hospital-SMZ-Ost, Vienna, Austria.
J Gastrointest Surg. 2008 May;12(5):921-5. doi: 10.1007/s11605-008-0485-z. Epub 2008 Feb 16.
Sacral nerve stimulation is a widely accepted therapeutic option for neurogenic fecal incontinence. More recently, case reports showed a positive effect of sacral nerve stimulation in patients with fecal incontinence following low anterior resection. The purpose of this study was to gain more information for this selected indication for sacral nerve stimulation through a nationwide survey.
In the period 2002 to 2005, three Austrian departments reported data of patients who underwent SNS for fecal incontinence following rectal resection. Data were available of seven patients (two female, five male) with a median age of 57 years (min 42; max 79). Six patients had undergone rectal resection as a treatment for low rectal cancer. One patient had undergone rectal resection for Crohn's disease, one patient subtotal colectomy and ileorectostomy for slow colon transit constipation.
Test stimulation was performed in the foramen S3 unilaterally over a median period of 14 days (2-21 days). Seven patients reported a marked reduction of episodes of incontinence during the observation period and received a permanent stimulation system. After a median follow-up of 32 months (17-46), five patients reported a marked improvement of their continence situation.
Despite a nationwide survey experiences with SNS as a treatment for fecal incontinence following rectal resection is still limited. Our observations show an improvement of the continence function following SNS. However, the promising results of our series as well as others need further research and more clinical data by a larger number of patients in a prospective trial.
骶神经刺激是神经源性大便失禁广泛接受的治疗选择。最近,病例报告显示骶神经刺激对低位前切除术后大便失禁患者有积极作用。本研究的目的是通过全国性调查获取更多关于骶神经刺激这一特定适应症的信息。
在2002年至2005年期间,奥地利的三个科室报告了因直肠切除术后大便失禁接受骶神经刺激治疗的患者数据。有7例患者(2例女性,5例男性)的数据,中位年龄为57岁(最小42岁;最大79岁)。6例患者因低位直肠癌接受直肠切除术。1例患者因克罗恩病接受直肠切除术,1例患者因结肠传输缓慢便秘接受次全结肠切除术和回肠直肠吻合术。
在S3孔单侧进行测试刺激,中位时间为14天(2 - 21天)。7例患者报告在观察期内失禁发作明显减少,并接受了永久性刺激系统。中位随访32个月(17 - 46个月)后,5例患者报告其控便情况有明显改善。
尽管进行了全国性调查,但骶神经刺激作为直肠切除术后大便失禁治疗方法的经验仍然有限。我们的观察显示骶神经刺激后控便功能有所改善。然而,我们系列以及其他研究的有前景的结果需要进一步研究,并通过更多患者的前瞻性试验获得更多临床数据。