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骶神经刺激治疗神经源性大便失禁。

Sacral nerve stimulation for neurogenic faecal incontinence.

作者信息

Holzer B, Rosen H R, Novi G, Ausch C, Hölbling N, Schiessel R

机构信息

Department of Surgery, Danube Hospital, Sozialmedizinisches Zentrum Ost, Vienna, Austria.

出版信息

Br J Surg. 2007 Jun;94(6):749-53. doi: 10.1002/bjs.5499.

Abstract

BACKGROUND

Sacral nerve stimulation (SNS) has emerged as a promising technique for the treatment of faecal incontinence. This study assessed the outcome of SNS in a cohort of patients with incontinence of neurological aetiology.

METHODS

Thirty-six patients were included in a trial of SNS. Twenty-nine subsequently had a permanent implant. Evaluation consisted of a continence diary, anal manometry, saline retention testing and quality of life assessment.

RESULTS

After a median follow-up of 35 (range 3-71) months, 28 patients showed a marked improvement in or complete recovery of continence. Incontinence to solid or liquid stool decreased from a median of 7 (range 4-15) to 2 (range 0-5) episodes in 21 days (P = 0.002). Saline retention time increased from a median of 2 (range 0-5) to 7 (range 2-15) min (P = 0.002). Maximum resting and squeeze anal canal pressures increased compared with preoperative values. Quality of life on all scales among patients who received a permanent implant increased at 12 and 24 months after operation.

CONCLUSION

SNS is of value in selected patients with neurogenic faecal incontinence.

摘要

背景

骶神经刺激(SNS)已成为一种治疗大便失禁的有前景的技术。本研究评估了SNS在一组神经源性病因导致失禁的患者中的治疗效果。

方法

36名患者纳入SNS试验。其中29名随后接受了永久性植入。评估包括控便日记、肛门测压、盐水潴留试验和生活质量评估。

结果

中位随访35(范围3 - 71)个月后,28名患者的控便能力有显著改善或完全恢复。21天内固体或液体粪便失禁次数从中位值7次(范围4 - 15次)降至2次(范围0 - 5次)(P = 0.002)。盐水潴留时间从中位值2分钟(范围0 - 5分钟)增加到7分钟(范围2 - 15分钟)(P = 0.002)。与术前值相比,最大静息和收缩肛管压力增加。接受永久性植入的患者在术后12个月和24个月时所有量表上的生活质量均有所提高。

结论

SNS对部分神经源性大便失禁患者有价值。

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