Kasap Belde, Duman Nuray, Ozer Esra, Tatli Mansur, Kumral Abdullah, Ozkan Hasan
Department of Pediatrics, Faculty of Medicine, Dokuz Eylül University, Inciralti, Izmir, Turkey.
Pediatr Int. 2008 Feb;50(1):81-4. doi: 10.1111/j.1442-200X.2007.02535.x.
Because there is a lack of well-established criteria, the aim of the present paper was to determine risk factors to predict the duration of tachypnea in transient tachypnea of the newborn (TTN).
Data from 95 newborns with TTN were evaluated retrospectively. Clinical and laboratory findings were compared between patients in whom tachypnea lasted <72 h (group 1) or >72 h (group 2).
Male gender, prematurity and delivery by cesarean section were the major risk factors for TTN. Parenteral furosemide had no effect on the clinical course. Peak respiratory rate (RRpeak) at the first 36 h was significantly higher in group 2 (P > 0.000). The cut-off for RRpeak during the first 36 h (RRpeak36) was 90/min and RRpeak36 > 90/min caused a 7.04-fold risk of prolonged tachypnea. White blood cell count and hematocrit levels were lower whereas duration of hospitalization and antibiotic treatment were longer in group 2.
Assessment of RRpeak36 may be useful in predicting clinical course of TTN.
由于缺乏成熟的标准，本文旨在确定预测新生儿短暂性呼吸急促（TTN）呼吸急促持续时间的危险因素。
回顾性评估95例TTN新生儿的数据。比较呼吸急促持续时间<72小时的患者（第1组）和>72小时的患者（第2组）的临床和实验室检查结果。
男性、早产和剖宫产是TTN的主要危险因素。静脉注射速尿对临床病程无影响。第2组在最初36小时的最高呼吸频率（RRpeak）显著更高（P>0.000）。最初36小时的RRpeak（RRpeak36）临界值为90次/分钟，RRpeak36>90次/分钟会导致呼吸急促延长的风险增加7.04倍。第2组的白细胞计数和血细胞比容水平较低，而住院时间和抗生素治疗时间较长。
评估RRpeak36可能有助于预测TTN的临床病程。
