剖宫产分娩患者中风风险增加：一项基于全国人口的研究。
Increased risk of stroke in patients who undergo cesarean section delivery: a nationwide population-based study.
作者信息
Lin Shiyng-Yu, Hu Chaur-Jong, Lin Herng-Ching
机构信息
Department of Family Practice, Taipei Medical University, Taipei, Taiwan, Republic of China.
出版信息
Am J Obstet Gynecol. 2008 Apr;198(4):391.e1-7. doi: 10.1016/j.ajog.2007.10.789. Epub 2008 Feb 14.
OBJECTIVE
This study used a population-based dataset to determine whether (compared with vaginal deliveries), cesarean section deliveries increase the risk of postpartum stroke during the 3-, 6-, or 12-month period after delivery.
STUDY DESIGN
This study used 1998-2003 records from the Taiwan National Health Insurance Research Database for 987,010 women with singleton deliveries from 1998-2002. Cox proportional hazard regressions were carried out to compute stroke-free survival rates between the 2 delivery modes.
RESULTS
The regression model indicated that, compared with patients who delivered vaginally, the hazard ratio for postpartum stroke among those who delivered by cesarean section was 1.67 times greater within 3 months of delivery (95% CI, 1.29-2.16), was 1.61 times greater within 6 months of delivery (95% CI, 1.31-1.98), and was 1.49 times greater within 12 months of delivery (95% CI, 1.27-1.76).
CONCLUSION
Our data indicates that cesarean section delivery is an independent risk factor for stroke.
目的
本研究使用基于人群的数据集来确定剖宫产分娩（与阴道分娩相比）是否会增加产后3个月、6个月或12个月内发生中风的风险。
研究设计
本研究使用了台湾国民健康保险研究数据库1998 - 2003年的记录，涉及1998 - 2002年单胎分娩的987,010名女性。进行Cox比例风险回归以计算两种分娩方式之间的无中风生存率。
结果
回归模型表明，与阴道分娩的患者相比，剖宫产分娩者产后3个月内发生中风的风险比高1.67倍（95%可信区间，1.29 - 2.16），产后6个月内高1.61倍（95%可信区间，1.31 - 1.98），产后12个月内高1.49倍（95%可信区间，1.27 - 1.76）。
结论
我们的数据表明剖宫产分娩是中风的独立危险因素。
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