Munguia Raymundo, Daniel Sam J
McGill Auditory Sciences Laboratory, McGill University, Montreal, Qc., Canada H3H1P3.
Int J Pediatr Otorhinolaryngol. 2008 Apr;72(4):453-9. doi: 10.1016/j.ijporl.2007.12.005. Epub 2008 Feb 14.
There has been an increase in the prevalence of otomycosis in recent years. This has been linked to the extensive use of antibiotic eardrops. Treatment of otomycosis is challenging, and requires a close follow-up. We present a review of the literature on otomycosis, the topical antifungals most commonly used, and discuss their ototoxic potential. Candida albicans and Aspergillus are the most commonly identified organisms. Antifungals from the Azole class seem to be the most effective, followed by Nystatin and Tolnaftate.
近年来,耳真菌病的患病率有所上升。这与抗生素滴耳液的广泛使用有关。耳真菌病的治疗具有挑战性,需要密切随访。我们对耳真菌病、最常用的局部抗真菌药物的文献进行了综述,并讨论了它们的耳毒性潜力。白色念珠菌和曲霉菌是最常见的病原体。唑类抗真菌药物似乎最有效,其次是制霉菌素和特比萘芬。