Perseke Marleen, Fritzsch Guido, Ramsch Kai, Bernt Matthias, Merkle Daniel, Middendorf Martin, Bernhard Detlef, Stadler Peter F, Schlegel Martin
Institute of Biology II: Zoologie, Molekulare Evolution und Systematik der Tiere, University of Leipzig, Talstrasse 33, D-04103 Leipzig, Germany.
Mol Phylogenet Evol. 2008 May;47(2):855-64. doi: 10.1016/j.ympev.2007.11.034. Epub 2007 Dec 15.
A comprehensive analysis of the mitochondrial gene orders of all previously published and two novel Antedon mediterranea (Crinoidea) and Ophiura albida (Ophiuroidea) complete echinoderm mitochondrial genomes shows that all major types of rearrangement operations are necessary to explain the evolution of mitochondrial genomes. In addition to protein coding genes we include all tRNA genes as well as the control region in our analysis. Surprisingly, 7 of the 16 genomes published in the GenBank database contain misannotations, mostly unannotated tRNAs and/or mistakes in the orientation of tRNAs, which we have corrected here. Although the gene orders of mt genomes appear very different, only 8 events are necessary to explain the evolutionary history of echinoderms with the exception of the ophiuroids. Only two of these rearrangements are inversions, while we identify three tandem-duplication-random-loss events and three transpositions.
对所有先前已发表的以及两种新的地中海海羊齿（海百合纲）和白蛇尾（蛇尾纲）完整棘皮动物线粒体基因组的线粒体基因排列进行的全面分析表明，所有主要类型的重排操作对于解释线粒体基因组的进化都是必要的。在我们的分析中，除了蛋白质编码基因外，还包括所有的tRNA基因以及控制区。令人惊讶的是，GenBank数据库中已发表的16个基因组中有7个存在注释错误，大多是未注释的tRNA和/或tRNA方向错误，我们在此已进行了纠正。尽管线粒体基因组的基因排列看起来非常不同，但除蛇尾类外，仅需8个事件就能解释棘皮动物的进化历史。这些重排中只有两个是倒位，而我们识别出三个串联重复-随机丢失事件和三个转座事件。
