Relationship between thyroid status and renal function in a general population of unselected outpatients.

作者信息

Lippi Giuseppe, Montagnana Martina, Targher Giovanni, Salvagno Gian Luca, Guidi Gian Cesare

机构信息

Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico-Biomediche, Università di Verona, Italy.

出版信息

Clin Biochem. 2008 May;41(7-8):625-7. doi: 10.1016/j.clinbiochem.2008.01.014. Epub 2008 Feb 5.

OBJECTIVE

To investigate the relationship between thyroid and kidney function.

DESIGN AND METHODS

13,383 results of serum creatinine and thyroid stimulating hormone (TSH) were retrieved from the database of our Laboratory.

RESULTS

When compared with euthyroid subjects, those with TSH <0.2 mIU/L and >2.5 mIU/L had increased and decreased estimated glomerular filtration rate (e-GFR), respectively. TSH levels were an independent predictor of e-GFR.

CONCLUSIONS

A mutual relationship was observed between kidney and thyroid status.