Davis Mark D P, Wysokinski Waldemar E
Department of Dermatology, Mayo Clinic, Rochester, Minnesota 55905, USA.
J Am Acad Dermatol. 2008 Mar;58(3):512-5. doi: 10.1016/j.jaad.2006.04.087.
A 50-year-old woman had a lifelong history of painful ulcerations as a result of livedoid vasculopathy. She was a heterozygous carrier of factor V Leiden and prothrombin gene mutations and was receiving hormone replacement therapy. The ulcers healed after warfarin therapy, which has been reported to be effective in only one previous patient with this condition.
一名50岁女性因萎缩性硬化性苔藓样血管病终生患有疼痛性溃疡。她是因子V莱顿突变和凝血酶原基因突变的杂合子携带者,正在接受激素替代疗法。华法林治疗后溃疡愈合,此前仅有1例该疾病患者接受此治疗有效。