Caramia Giuseppe, Atzei Alessandra, Fanos Vassilios
Pediatric Department, Salesi Hospital, Ancona, Italy.
Clin Dermatol. 2008 Jan-Feb;26(1):4-11. doi: 10.1016/j.clindermatol.2007.10.008.
A review of the relationships between probiotics and the skin is presented. After a brief historical introduction, the main pathophysiological data on intestinal microflora, the immune system and the skin are presented. Clinical studies with probiotics in atopic children are discussed in detail. Many experimental studies have found that probiotics exert specific effects in the luminal lumen and on epithelial cells and immune cells with antiallergic potential. Not all probiotics have the same immunological properties. Moreover, although rarely, complications of probiotic use can occur and must be known and taken into account. This review underlines the potential interest in probiotics for the management of skin pathology.
本文综述了益生菌与皮肤之间的关系。在简要介绍历史背景后,阐述了关于肠道微生物群、免疫系统和皮肤的主要病理生理学数据。详细讨论了益生菌用于特应性儿童的临床研究。许多实验研究发现,益生菌在管腔内以及对具有抗过敏潜力的上皮细胞和免疫细胞发挥特定作用。并非所有益生菌都具有相同的免疫学特性。此外,尽管很少见,但使用益生菌可能会出现并发症,必须予以了解并加以考虑。本综述强调了益生菌在皮肤疾病管理方面的潜在价值。