由于枸杞可能产生的影响导致华法林过量

Warfarin overdose due to the possible effects of Lycium barbarum L.

作者信息

Leung H, Hung A, Hui A C F, Chan T Y K

机构信息

Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong.

出版信息

Food Chem Toxicol. 2008 May;46(5):1860-2. doi: 10.1016/j.fct.2008.01.008. Epub 2008 Jan 15.

DOI:10.1016/j.fct.2008.01.008

PMID:18281140

Abstract

We reported an 80-year-old Chinese woman on chronic stable dose of warfarin who experienced two episodes of an elevated international normalized ratio (INR) after drinking herbal tea containing Lycium barbarum L. Our case illustrated the potential herbal-drug interaction between warfarin and L. barbarum L. in keeping with a previous case report. Enquiry about herbal intake may be a crucial part in the management of anticoagulation in this locality.

摘要

我们报告了一名80岁的中国女性，她长期服用稳定剂量的华法林，在饮用了含有枸杞的草药茶后出现了两次国际标准化比值（INR）升高的情况。我们的病例表明了华法林与枸杞之间潜在的草药-药物相互作用，这与之前的一份病例报告一致。在该地区，询问草药摄入情况可能是抗凝管理中的关键环节。