Colen Tahl Y, Seidman Carly, Weedon Jeremy, Goldstein Nira A
Division of Pediatric Otolaryngology, State University of New York Downstate Medical Center, Brooklyn, NY 11203, USA.
Arch Otolaryngol Head Neck Surg. 2008 Feb;134(2):124-7. doi: 10.1001/archoto.2007.8.
To assess the change in disease-specific quality of life (QOL) in pediatric patients with obstructive sleep-disordered breathing (OSDB) secondary to adenotonsillar hypertrophy after powered intracapsular tonsillectomy and adenoidectomy.
Prospective outcomes study.
Hospital-based pediatric otolaryngology practice.
Fifty children with a mean age of 4.5 years who had a clinical diagnosis of OSDB.
A caregiver of qualifying patients completed a validated QOL survey of pediatric obstructive sleep apnea, the OSA-18 (Obstructive Sleep Apnea-18), preoperatively and 3 months and 1 year postoperatively.
The OSA-18 mean change scores.
The mean (SD) total OSA-18 change score at the 3-month follow-up visit was 2.3 (1.2) and at the 1 year follow-up visit was 2.2 (1.3). The total and individual domain change scores were significantly improved at both postoperative intervals (P<.001 for all). There were no significant changes in the total or domain change scores between the intervals. The total change score was not significantly associated with either tonsil size or tonsil position.
The OSDB-related QOL is significantly improved after powered intracapsular tonsillectomy and adenoidectomy, and this improvement remains stable even after 1 year.
评估因腺样体扁桃体肥大继发阻塞性睡眠呼吸障碍（OSDB）的儿科患者在动力囊内扁桃体切除术和腺样体切除术后疾病特异性生活质量（QOL）的变化。
前瞻性结局研究。
以医院为基础的儿科耳鼻喉科诊所。
50名平均年龄为4.5岁、临床诊断为OSDB的儿童。
符合条件患者的照料者在术前、术后3个月和1年完成一份经过验证的儿科阻塞性睡眠呼吸暂停生活质量调查问卷，即OSA-18（阻塞性睡眠呼吸暂停-18）。
OSA-18平均变化分数。
在3个月随访时，OSA-18总变化分数的均值（标准差）为2.3（1.2），在1年随访时为2.2（1.3）。在两个术后时间点，总分及各领域变化分数均有显著改善（所有P值均<0.001）。两个时间点之间，总分及领域变化分数均无显著变化。总变化分数与扁桃体大小或扁桃体位置均无显著相关性。
动力囊内扁桃体切除术和腺样体切除术后，与OSDB相关的生活质量显著改善，且这种改善即使在1年后仍保持稳定。
