Lee Jennifer L, Naguwa Stanley M, Cheema Gurtej S, Gershwin M Eric
Department of Internal Medicine, School of Medicine, University of California at Davis, Davis, CA 95616, USA.
Clin Rev Allergy Immunol. 2008 Oct;35(1-2):88-95. doi: 10.1007/s12016-008-8075-0.
Giant cell arteritis (GCA) is the most common vasculopathy in patients over the age of 50. The majority of data on the geo-epidemiology of GCA is derived from Scandinavia, although there is very good documentation and epidemiological descriptions from studies throughout Europe and North America. There remains, however, a paucity of data on the incidence and prevalence of GCA in North American minority populations, as well as from Africa or Asia. The data that does exist suggests that the incidence of GCA is lower in Hispanic, Asian, and African American populations. It is interesting to note that as the population throughout the world continues to age, we anticipate an increased prevalence of disease based upon increases in annual incidence and improved survival. Considerable research is still needed to identify genetic, environmental, and gender-specific factors that influence not only the etiology, but also the natural history of disease.
巨细胞动脉炎（GCA）是50岁以上患者中最常见的血管病。关于GCA地理流行病学的大多数数据来自斯堪的纳维亚半岛，尽管欧洲和北美的研究有非常完善的文献记录和流行病学描述。然而，关于北美少数族裔人群以及非洲或亚洲GCA发病率和患病率的数据仍然很少。现有的数据表明，西班牙裔、亚裔和非裔美国人中GCA的发病率较低。有趣的是，随着全球人口持续老龄化，基于年发病率的上升和生存率的提高，我们预计该病的患病率会增加。仍需要大量研究来确定不仅影响病因，而且影响疾病自然史的遗传、环境和性别特异性因素。
