Raby N, Karani J, Thomas S, O'Grady J, Williams R
Department of Radiology, Kings College Hospital, Denmark Hill, London, England.
AJR Am J Roentgenol. 1991 Jul;157(1):167-71. doi: 10.2214/ajr.157.1.1828649.
Vascular complications after liver transplantation include occlusion or stenosis at the sites of anastomosis in the hepatic artery, portal vein, and vena cava. From our experience with more than 600 liver transplants, vascular stenoses have been identified in 10 patients and treated by balloon angioplasty in nine. Three patients with hepatic artery stenosis and deteriorating graft function were treated by balloon angioplasty with a coaxial technique. A specially designed catheter facilitated a successful femoral artery approach. Portal vein stenoses in three patients resulted in portal hypertension. These were treated by balloon dilatation via transhepatic catheterization of the portal vein. Stenoses of the suprahepatic caval anastomosis were dilated in three patients with severe lower limb edema. Technical success was achieved in all three cases of hepatic artery stenosis with improvement in graft function. Recurrent stenoses in two patients were successfully treated with repeated dilatations. Portal hypertension resolved in two of three patients after portal venoplasty. Dilatation of a caval stenosis resulted in the resolution of leg edema in all three cases. Repeated dilatation was required in one case. No reduction in the portal venous pressure gradient occurred after venoplasty in one case, and an ultimately fatal caval thrombosis developed in one patient with caval stenosis before venoplasty could be performed. Our experience suggests that balloon angioplasty of arterial and venous stenoses complicating hepatic transplantation carries little risk and is a useful procedure for the treatment of these problems.
肝移植后的血管并发症包括肝动脉、门静脉和腔静脉吻合部位的闭塞或狭窄。根据我们超过600例肝移植的经验,已在10例患者中发现血管狭窄,其中9例通过球囊血管成形术进行了治疗。3例肝动脉狭窄且移植肝功能恶化的患者采用同轴技术进行球囊血管成形术治疗。一种专门设计的导管有助于成功经股动脉入路。3例患者的门静脉狭窄导致门静脉高压。这些患者通过经肝门静脉导管插入术进行球囊扩张治疗。3例严重下肢水肿患者的肝上腔静脉吻合口狭窄进行了扩张。3例肝动脉狭窄患者均取得技术成功,移植肝功能改善。2例患者的复发性狭窄通过重复扩张成功治疗。门静脉成形术后,3例患者中有2例门静脉高压得到缓解。腔静脉狭窄扩张后,3例患者的腿部水肿均得到缓解。1例患者需要重复扩张。1例患者门静脉成形术后门静脉压力梯度未降低,1例腔静脉狭窄患者在门静脉成形术能够实施之前发生了最终致命的腔静脉血栓形成。我们的经验表明,肝移植术后并发的动脉和静脉狭窄进行球囊血管成形术风险很小,是治疗这些问题的有效方法。