Dimmer Emily, Berardini Tanya Z, Barrell Daniel, Camon Evelyn
European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.
Methods Mol Biol. 2007;406:495-520. doi: 10.1007/978-1-59745-535-0_24.
The Gene Ontology (GO) is an established dynamic and structured vocabulary that has been successfully used in gene and protein annotation. Designed by biologists to improve data integration, GO attempts to replace the multiple nomenclatures used by specialised and large biological knowledgebases. This chapter describes the methods used by groups to create new GO annotations and how users can apply publicly available GO annotations to enhance their datasets.
基因本体论（GO）是一个已确立的动态结构化词汇表，已成功用于基因和蛋白质注释。GO由生物学家设计以改善数据整合，试图取代专业和大型生物知识库所使用的多种命名法。本章描述了各团队用于创建新的GO注释的方法，以及用户如何应用公开可用的GO注释来增强其数据集。
