Tranquart F, Bleuzen A, Pierre-Renoult P, Chabrolle C, Sam Giao M, Lecomte P
Service d'Ultrasons, CHRU Tours, Hôpital Bretonneau, 37044 Tours Cedex 1.
J Radiol. 2008 Jan;89(1 Pt 1):35-9. doi: 10.1016/s0221-0363(08)70367-6.
While ultrasound is the imaging modality of choice for diagnosis of thyroid lesions, characterization remains limited and tissue diagnosis frequently is required for management. The availability of additional tools such as elastography may improve lesion characterization and direct management.
A total of 96 patients (11 males and 85 females; 58+/-24 years) referred for fine needle aspiration (FNA) of mainly solid thyroid nodules 9-32 mm in diameter underwent conventional US and elastosonography. Results on elastography were correlated with histological results from FNA and classified as follows: suspected malignant lesion, suspected benign lesion, suspicious, indeterminate.
The nodules were classified as follows: 95 nodules were soft (classes I and II) and 13 nodules were hard (classes III and IV). No cancers were detected in class and II lesions and 6 cancers were detected in class III and IV lesions. FNA provided insufficient cellular material for diagnosis in 5 class I-II nodules and 2 class III-IV nodules.
Real-time elastosonography may be a useful adjunct to conventional US in the evaluation and characterization of thyroid nodules allowing identification of patients at high risk of malignancy for whom tissue diagnosis and/or close follow-up is required.
虽然超声是诊断甲状腺病变的首选成像方式,但特征描述仍然有限,组织诊断对于治疗通常是必需的。弹性成像等其他工具的可用性可能会改善病变特征描述并指导治疗。
总共96例患者(11例男性和85例女性;年龄58±24岁)因主要为直径9 - 32毫米的实性甲状腺结节接受细针穿刺活检(FNA),并接受了传统超声和弹性超声检查。弹性成像结果与FNA的组织学结果相关,并分类如下:疑似恶性病变、疑似良性病变、可疑、不确定。
结节分类如下:95个结节为软结节(I类和II类),13个结节为硬结节(III类和IV类)。I类和II类病变中未检测到癌症,III类和IV类病变中检测到6例癌症。FNA在5个I - II类结节和2个III - IV类结节中提供的细胞材料不足以进行诊断。
实时弹性超声在甲状腺结节的评估和特征描述中可能是传统超声的有用辅助手段,有助于识别需要进行组织诊断和/或密切随访的高恶性风险患者。