Moghadam B K, Drisko C L, Gier R E
Department of Oral Diagnosis and Radiology, University of Missouri, Kansas City.
Oral Surg Oral Med Oral Pathol. 1991 Apr;71(4):431-4. doi: 10.1016/0030-4220(91)90424-b.
Various adverse reactions including anaphylactic shock have already been reported after the topical application of chlorhexidine. This article reports for the first time a hypersensitivity reaction in the form of fixed drug eruption after the use of a mouthwash containing chlorhexidine. This report should bring an increased awareness of the possibility of systemic hypersensitivity reaction to chlorhexidine in a previously sensitized person. The report also will add fixed drug eruption to the list of skin hypersensitivity reactions caused by chlorhexidine.
外用洗必泰后已报告了包括过敏性休克在内的各种不良反应。本文首次报告了使用含洗必泰漱口水后出现的固定性药疹形式的过敏反应。本报告应提高人们对既往致敏个体对洗必泰发生全身性过敏反应可能性的认识。该报告还将固定性药疹添加到由洗必泰引起的皮肤过敏反应列表中。
