Chopra Viresh, Chopra Harneet, Sharma Anamika
Department of Conservative and Endodontics, Subharti Dental College, Meerut, Uttar Pradesh, India.
Indian J Dermatol. 2013 Jan;58(1):85. doi: 10.4103/0019-5154.105323.
Chlorhexidine is a widely used antiseptic and disinfectant in medical and non-medical environments. Compared to its ubiquitous use, allergic contact dermatitis from chlorhexidine has rarely been reported and so its sensitization rate seems to be low. Chlorhexidine has been used for more than 50 years but it was only in the last two decades, that reports of immediate- type reactions to chlorhexidine were seen. Reactions ranging from localized urticaria to anaphylactic shock and hypersensitivity reactions, including delayed hypersensitivity reactions such as contact dermatitis, fixed drug eruptions, and photosensitivity reactions, began to appear more frequently. However the prevalence of contact urticaria and anaphylaxis due to chlorhexidine remains to be unknown. In this case report we have reported a case of urticaria due to oral use of chlorhexidine. The adverse reaction was confirmed by a skin prick test.
洗必泰是一种在医疗和非医疗环境中广泛使用的防腐剂和消毒剂。与其广泛使用相比,洗必泰引起的过敏性接触性皮炎报道很少,因此其致敏率似乎较低。洗必泰已使用了50多年,但直到最近二十年,才出现对洗必泰速发型反应的报道。从局部荨麻疹到过敏性休克以及超敏反应,包括接触性皮炎、固定性药疹和光敏反应等迟发型超敏反应开始更频繁地出现。然而,洗必泰引起的接触性荨麻疹和过敏反应的患病率仍不清楚。在本病例报告中,我们报告了一例因口服洗必泰引起荨麻疹的病例。皮肤点刺试验证实了该不良反应。