Shiba Yuji, Takahashi Masafumi, Ikeda Uichi
Department of Cardiovascular Medicine, Shinshu University Graduate School of Medicine, Matsumoto, Japan.
Curr Pharm Des. 2008;14(4):371-7. doi: 10.2174/138161208783497741.
Cardiovascular disease remains a principal cause of mortality in Western countries. Novel strategies for enhancing angiogenesis (such as gene or cell therapy) provide alternative choices for patients without any current treatment options. This progress has contributed towards understanding the mechanisms underlying vascular formation. The establishment of new experimental models could lead to the development of new treatments. This article overviews the diverse models for the study of angiogenesis.
心血管疾病仍然是西方国家主要的死亡原因。增强血管生成的新策略（如基因或细胞疗法）为目前没有任何治疗选择的患者提供了替代方案。这一进展有助于理解血管形成的潜在机制。新实验模型的建立可能会带来新治疗方法的开发。本文概述了用于研究血管生成的多种模型。
