Wehling M, Lössl M, Theisen K, Frey A
Medizinische Klinik, Klinikum Innenstadt, München.
Z Kardiol. 1991 Feb;80(2):144-8.
In 15 patients with essential hypertension, anginal pain, and angiographically excluded coronary artery disease 24-h monitoring of the ST-segment and blood pressure was performed. 26 episodes with ST-segment depressions 0400.1 mV were recorded in 11/15 patients. In 10/26 episodes with ST-segment depressions blood pressure was elevated above 150/95 mm Hg or by more than 20% as compared to three successive measurements before the ST-segment depressions. Heart rate was increased by more than 20% in 20/26 ST-segment depressions. During 9 periods with ST-segment depressions angina pectoris was reported; in addition 27 anginal attacks without ST-segment depressions were observed. A significant, positive correlation between the diastolic (p less than 0.005) and systolic (p less than 0.02) blood pressure and the extent of the ST-segment depression was observed. These correlations imply a patho-physiological meaning of ST-segment depressions in hypertensive patients.
对15例患有原发性高血压、心绞痛且经血管造影排除冠状动脉疾病的患者进行了ST段和血压的24小时监测。11/15例患者记录到26次ST段压低≥0.1mV的发作。在26次ST段压低发作中的10次,血压升高超过150/95mmHg,或与ST段压低前连续三次测量相比升高超过20%。26次ST段压低中的20次心率增加超过20%。在9次ST段压低期间报告有心绞痛;此外,还观察到27次无ST段压低的心绞痛发作。观察到舒张压(p<0.005)和收缩压(p<0.02)与ST段压低程度之间存在显著的正相关。这些相关性提示了高血压患者ST段压低的病理生理意义。