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[成功手术切除侵犯下腔静脉及右心房的肾上腺皮质癌]

[Successful surgical removal of adrenocortical carcinoma growing into the inferior vena cava and the right atrium].

作者信息

Péterffy Arpád, Dezso Balázs, Adler Ildikó, Arkossy Péter, Szerafin Tamás

机构信息

Szívsebészeti Központ Debreceni Egyetem, Orvos- és Egészségtudományi Centrum Kardiológiai Intézet, 4004 Debrecen, Móricz Zs. krt. 22.

出版信息

Magy Seb. 2008 Feb;61(1):38-41. doi: 10.1556/MaSeb.61.2008.1.8.

Abstract

The authors discuss a case of a 47-year old female, who underwent a left adrenalectomy for adrenocortical carcinoma. A few months later the tumour locally recurred and spread through the inferior vena cava into the right atrium. The tumour thrombus almost completely occluded the lumen of the inferior vena cava resulting in significant hepatic congestion, ascites and oedema of the lower extremities. The whole tumour thrombus was successfully removed through the right atrium under visual control using extracorporeal circulation in deep hypothermic (20 degrees C) circulatory arrest. The locally recurred tumour from the site of the left adrenal gland was also removed a month later. The histological examination revealed moderately differentiated adrenocortical carcinoma with a proliferation rate higher than 10%. Thereafter, patient underwent adjuvant oncological therapy and she has been disease free in the last one year. Clinical data suggest that tumour thrombus of various origin that grow into the inferior vena cava can be safely removed using extracorporeal circulation (with or without cardiac arrest), and in such cases, when the primary tumour is resectable, the prognosis is relatively good.

摘要

作者讨论了一例47岁女性患者,该患者因肾上腺皮质癌接受了左肾上腺切除术。几个月后,肿瘤局部复发并通过下腔静脉扩散至右心房。肿瘤血栓几乎完全阻塞了下腔静脉管腔,导致严重的肝淤血、腹水和下肢水肿。在体外循环下,于深低温(20℃)循环停止状态下,通过可视控制经右心房成功取出了整个肿瘤血栓。一个月后,还切除了来自左肾上腺部位的局部复发性肿瘤。组织学检查显示为中度分化的肾上腺皮质癌,增殖率高于10%。此后,患者接受了辅助肿瘤治疗,在过去一年中病情无复发。临床数据表明,各种起源并长入下腔静脉的肿瘤血栓可通过体外循环(有或无心脏停搏)安全取出,在这种情况下,当原发性肿瘤可切除时,预后相对较好。

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