外周神经元上抑制性和兴奋性突触电位之间的相互作用。
Interaction between inhibitory and excitatory synaptic potentials at a peripheral neurone.
作者信息
Edwards F R, Hirst G D, Silinsky E M
出版信息
J Physiol. 1976 Aug;259(3):647-63. doi: 10.1113/jphysiol.1976.sp011487.
Abstract
- The interaction between inhibitory and excitatory synaptic potentials in neurones lying in the submucous plexus of guinea-pig ileum has been examined. 2. It was found that during an inhibitory conductance change, electrotonic potentials were more depressed in amplitude than were excitatory synaptic potentials. 3. It is suggested that inhibitory conductance changes may have only a slight effect on the impedance seen by excitatory synaptic currents as much of the excitatory synaptic current flow is likely to be capacitive. 4. A part of the depression of excitatory synaptic potential amplitude was not associated with changes in electrical properties of neurones and it is suggested that inhibitory transmitter may reduce the release of excitatory transmitter.
摘要
- 对豚鼠回肠黏膜下神经丛中神经元的抑制性和兴奋性突触电位之间的相互作用进行了研究。2. 发现，在抑制性电导变化期间，电紧张电位的幅度比兴奋性突触电位的幅度更易被抑制。3. 有人提出，抑制性电导变化可能对兴奋性突触电流所看到的阻抗只有轻微影响，因为大部分兴奋性突触电流可能是电容性的。4. 兴奋性突触电位幅度的部分抑制与神经元电特性的变化无关，有人提出抑制性递质可能会减少兴奋性递质的释放。
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