• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

从豚鼠小肠黏膜下神经丛神经元记录到的突触电位。

Synaptic potentials recorded from neurones of the submucous plexus of guinea-pig small intestine.

作者信息

Hirst G D, McKirdy H C

出版信息

J Physiol. 1975 Jul;249(2):369-85. doi: 10.1113/jphysiol.1975.sp011020.

DOI:10.1113/jphysiol.1975.sp011020
PMID:1177096
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1309579/
Abstract
  1. Intracellular recordings have been made from neurones lying in the submucous plexus of guinea-pig mid small intestine. 2. Most neurones in this plexus receive an extensive excitatory input which could be abolished by tubocurarine. 3. A proportion of neurones also received a single inhibitory input which was activated by transmural stimulation. 4. Some of the characteristics of the inhibitory potentials evoked by transmural stimulation are described. 5. The observations are discussed in relation to the concept of descending excitation (Hirst, Holman & McKirdy, 1975).
摘要
  1. 已对豚鼠中小肠黏膜下神经丛中的神经元进行了细胞内记录。2. 该神经丛中的大多数神经元接受广泛的兴奋性输入，这种输入可被筒箭毒碱消除。3. 一部分神经元还接受单一的抑制性输入，该输入由透壁刺激激活。4. 描述了透壁刺激诱发的抑制性电位的一些特征。5. 根据下行兴奋的概念（赫斯特、霍尔曼和麦基尔迪，1975年）对这些观察结果进行了讨论。
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aeba/1309579/3696d06eea0f/jphysiol00891-0204-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aeba/1309579/7c2d6da9d342/jphysiol00891-0204-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aeba/1309579/c12d9a67db4c/jphysiol00891-0204-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aeba/1309579/3696d06eea0f/jphysiol00891-0204-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aeba/1309579/7c2d6da9d342/jphysiol00891-0204-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aeba/1309579/c12d9a67db4c/jphysiol00891-0204-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aeba/1309579/3696d06eea0f/jphysiol00891-0204-c.jpg

相似文献

1
Synaptic potentials recorded from neurones of the submucous plexus of guinea-pig small intestine.从豚鼠小肠黏膜下神经丛神经元记录到的突触电位。
J Physiol. 1975 Jul;249(2):369-85. doi: 10.1113/jphysiol.1975.sp011020.
2
Synaptic inputs to immunohistochemically identified neurones in the submucous plexus of the guinea-pig small intestine.豚鼠小肠黏膜下神经丛中经免疫组织化学鉴定的神经元的突触输入
J Physiol. 1986 Dec;381:465-82. doi: 10.1113/jphysiol.1986.sp016339.
3
Two types of neurones lacking synaptic input in the submucous plexus of guinea-pig small intestine.豚鼠小肠黏膜下神经丛中两种缺乏突触输入的神经元。
J Physiol. 1984 Jun;351:363-78. doi: 10.1113/jphysiol.1984.sp015250.
4
A nervous mechanism for descending inhibition in guinea-pig small intestine.豚鼠小肠下行抑制的神经机制。
J Physiol. 1974 Apr;238(1):129-43. doi: 10.1113/jphysiol.1974.sp010514.
5
Intrinsic and extrinsic inhibitory synaptic inputs to submucous neurones of the guinea-pig small intestine.豚鼠小肠黏膜下神经元的内在和外在抑制性突触输入。
J Physiol. 1988 Apr;398:371-90. doi: 10.1113/jphysiol.1988.sp017048.
6
Synaptic potentials recorded from some neurones of the submucous plexus of guinea-pig intestine.
J Physiol. 1975 Jan;244(1):35P-36P.
7
Slow excitatory synaptic potentials recorded from neurones of guinea-pig submucous plexus.从豚鼠黏膜下神经丛神经元记录到的缓慢兴奋性突触电位。
J Physiol. 1984 Jun;351:343-61. doi: 10.1113/jphysiol.1984.sp015249.
8
Inhibitory synaptic potentials recorded from mammalian neurones prolonged by blockade of noradrenaline uptake.通过阻断去甲肾上腺素摄取延长从哺乳动物神经元记录到的抑制性突触电位。
J Physiol. 1987 Jan;382:87-103. doi: 10.1113/jphysiol.1987.sp016357.
9
Inhibitory synaptic potentials resulting from alpha 2-adrenoceptor activation in guinea-pig submucous plexus neurones.豚鼠黏膜下神经丛神经元中α2 -肾上腺素能受体激活所产生的抑制性突触电位。
J Physiol. 1985 Jan;358:17-33. doi: 10.1113/jphysiol.1985.sp015537.
10
Some effects of 5-hydroxytryptamine, dopamine and noradrenaline on neurones in the submucous plexus of guinea-pig small intestine.5-羟色胺、多巴胺和去甲肾上腺素对豚鼠小肠黏膜下神经丛神经元的某些作用。
J Physiol. 1975 Oct;251(3):817-32. doi: 10.1113/jphysiol.1975.sp011124.

引用本文的文献

1
The Imperative for Innovative Enteric Nervous System-Intestinal Organoid Co-Culture Models: Transforming GI Disease Modeling and Treatment.创新肠神经系统-肠类器官共培养模型的必要性：改变胃肠道疾病建模和治疗。
Cells. 2024 May 10;13(10):820. doi: 10.3390/cells13100820.
2
Culture of Neurons and Smooth Muscle Cells from the Myenteric Plexus of Adult Mice.成年小鼠肌间神经丛神经元和平滑肌细胞的培养
Methods Mol Biol. 2018;1727:119-125. doi: 10.1007/978-1-4939-7571-6_9.
3
Nitric oxide enhances inhibitory synaptic transmission and neuronal excitability in Guinea-pig submucous plexus.

本文引用的文献

1
Two types of neurones in the myenteric plexus of duodenum in the guinea-pig.豚鼠十二指肠肌间神经丛中的两种神经元。
J Physiol. 1974 Jan;236(2):303-26. doi: 10.1113/jphysiol.1974.sp010436.
2
Origin and blockade of the synaptic responses of curarized sympathetic ganglia.箭毒处理的交感神经节突触反应的起源与阻断
J Physiol. 1961 Aug;157(3):484-503. doi: 10.1113/jphysiol.1961.sp006738.
3
Transmission from intramural inhibitory nerves to the smooth muscle of the guinea-pig taenia coli.豚鼠结肠带平滑肌中壁内抑制性神经的传递。
一氧化氮增强豚鼠黏膜下神经丛的抑制性突触传递和神经元兴奋性。
Front Neurosci. 2010 May 21;4:30. doi: 10.3389/fnins.2010.00030.
4
5-HT(1A), SST(1), and SST(2) receptors mediate inhibitory postsynaptic potentials in the submucous plexus of the guinea pig ileum.5-HT(1A)、SST(1)和 SST(2)受体介导豚鼠回肠黏膜下神经丛中的抑制性突触后电位。
Am J Physiol Gastrointest Liver Physiol. 2010 Mar;298(3):G384-94. doi: 10.1152/ajpgi.00438.2009. Epub 2009 Dec 10.
5
Optical recording of electrical activity in guinea-pig enteric networks using voltage-sensitive dyes.使用电压敏感染料对豚鼠肠内神经网络中的电活动进行光学记录。
J Vis Exp. 2009 Dec 4(34):1631. doi: 10.3791/1631.
6
Synaptic transmission at functionally identified synapses in the enteric nervous system: roles for both ionotropic and metabotropic receptors.在肠神经系统中具有功能鉴定的突触的突触传递：离子型和代谢型受体的作用。
Curr Neuropharmacol. 2007 Mar;5(1):1-17. doi: 10.2174/157015907780077141.
7
Modulation of voltage-dependent Ba2+ currents in the guinea-pig gastric antrum by cyclic nucleotide-dependent pathways.环核苷酸依赖性途径对豚鼠胃窦中电压依赖性Ba2+电流的调节作用
Br J Pharmacol. 2005 Sep;146(1):129-38. doi: 10.1038/sj.bjp.0706295.
8
ATP participates in three excitatory postsynaptic potentials in the submucous plexus of the guinea pig ileum.三磷酸腺苷参与豚鼠回肠黏膜下神经丛中的三种兴奋性突触后电位。
J Physiol. 2004 Apr 15;556(Pt 2):571-84. doi: 10.1113/jphysiol.2004.060848. Epub 2004 Feb 13.
9
Long vasodilator reflexes projecting through the myenteric plexus in guinea-pig ileum.通过豚鼠回肠肌间神经丛投射的长血管舒张反射。
J Physiol. 2003 Dec 15;553(Pt 3):911-24. doi: 10.1113/jphysiol.2003.053140. Epub 2003 Oct 10.
10
Spatiotemporal patterns of activity in an intact mammalian network with single-cell resolution: optical studies of nicotinic activity in an enteric plexus.具有单细胞分辨率的完整哺乳动物网络中的时空活动模式：肠神经丛中烟碱活性的光学研究。
J Neurosci. 1999 Apr 15;19(8):3073-93. doi: 10.1523/JNEUROSCI.19-08-03073.1999.
J Physiol. 1966 Feb;182(3):541-58. doi: 10.1113/jphysiol.1966.sp007836.
4
Electrolyte distribution in rabbit superior cervical ganglion.
J Neurochem. 1969 Mar;16(3):289-99. doi: 10.1111/j.1471-4159.1969.tb10367.x.
5
The interpretation of current-voltage relations recorded from a spherical cell with a single microelectrode.用单个微电极从球形细胞记录的电流-电压关系的解释。
Biophys J. 1972 Apr;12(4):384-403. doi: 10.1016/S0006-3495(72)86091-0.
6
Presynaptic inhibition at mammalian peripheral synapse?哺乳动物外周突触处的突触前抑制？
Nature. 1974 Aug 2;250(465):430-1. doi: 10.1038/250430a0.
7
Intracellular recording from the myenteric plexus of the guinea-pig ileum.豚鼠回肠肌间神经丛的细胞内记录。
J Physiol. 1973 Jun;231(3):471-91. doi: 10.1113/jphysiol.1973.sp010244.
8
Cyclic variation of potassium conductance in a burst-generating neurone in Aplysia.海兔爆发式发放神经元中钾离子电导的周期性变化
J Physiol. 1973 Nov;235(1):155-81. doi: 10.1113/jphysiol.1973.sp010382.
9
Chemical transmission in invertebrate central nervous systems and neuromuscular junctions.无脊椎动物中枢神经系统和神经肌肉接头中的化学传递。
Physiol Rev. 1973 Jan;53(1):1-119. doi: 10.1152/physrev.1973.53.1.1.
10
An analysis of the uptake of 5-hydroxytryptamine by the myenteric plexus of the small intestine of the guinea pig.豚鼠小肠肌间神经丛对5-羟色胺摄取的分析。
J Pharmacol Exp Ther. 1971 Oct;179(1):29-41.