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早期脂肪乳剂治疗可能预防了布比卡因相关的心脏骤停。

Early intralipid therapy may have prevented bupivacaine-associated cardiac arrest.

作者信息

McCutchen Thomas, Gerancher J C

机构信息

Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

出版信息

Reg Anesth Pain Med. 2008 Mar-Apr;33(2):178-80. doi: 10.1016/j.rapm.2007.09.006.

Abstract

OBJECTIVE

Local anesthetic-induced cardiotoxicity remains a complication of regional anesthesia, with the potential to result in cardiac arrest refractory to resuscitation. Successful resuscitation using Intralipid (Baxter Pharmaceuticals by Fresenius Kabi, Uppsala, Sweden), has been reported in 2 patients with bupivacaine-induced cardiac arrest.

CASE REPORT

We report another case for which Intralipid was used as part of a successful resuscitation in a patient with local anesthetic-induced cardiotoxicity.

CONCLUSIONS

Early treatment with Intralipid may help prevent cardiac arrest and speed successful resuscitation efforts.

摘要

目的

局部麻醉药引起的心脏毒性仍然是区域麻醉的一种并发症,有可能导致难以复苏的心脏骤停。据报道,2例布比卡因引起心脏骤停的患者使用脂质乳剂(瑞典乌普萨拉费森尤斯卡比公司生产的百特制药产品)成功复苏。

病例报告

我们报告另一例局部麻醉药引起心脏毒性的患者,脂质乳剂作为成功复苏的一部分被使用。

结论

早期使用脂质乳剂治疗可能有助于预防心脏骤停并加速成功复苏。

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