重症肌无力患者的胸腺外恶性肿瘤。

Extrathymic malignancy in patients with myasthenia gravis.

作者信息

Monden Y, Uyama T, Kimura S, Taniki T

机构信息

Second Department of Surgery, School of Medicine, University of Tokushima, Japan.

出版信息

Eur J Cancer. 1991;27(6):745-7. doi: 10.1016/0277-5379(91)90179-h.

DOI:10.1016/0277-5379(91)90179-h

PMID:1829916

Abstract

The presence of extrathymic malignancies was investigated in 296 thymectomised myasthenia gravis (MG) cases. In 5 of the 296 cases, extrathymic malignant tumours were observed. 4 of the 5 cases had thymomatous MG. 3 cases had malignant fibrous histiocytoma. Extrathymic malignancies were observed more frequently in thymomatous MG than in non-thymomatous MG. 59 cases (60 tumours), including our 5 cases, who had MG and extrathymic malignant tumours were compiled from the literature. In the 60 extrathymic malignancies, leukaemia and reticulo-endothelial sarcoma were the most frequent types.

摘要

在296例接受胸腺切除术的重症肌无力（MG）患者中，对其是否存在胸腺外恶性肿瘤进行了调查。在这296例患者中，有5例观察到胸腺外恶性肿瘤。这5例患者中有4例患有胸腺瘤型MG。3例患有恶性纤维组织细胞瘤。胸腺瘤型MG患者中胸腺外恶性肿瘤的发生率高于非胸腺瘤型MG患者。从文献中收集了59例（60个肿瘤）患有MG和胸腺外恶性肿瘤的患者，包括我们的5例。在这60例胸腺外恶性肿瘤中，白血病和网状内皮肉瘤是最常见的类型。