Yoshizumi Jyun, Kumamoto Satoshi, Nakamura Mitsunobu, Yamana Kazushige
Department of Materials Science and Chemistry, Graduate School of Engineering, University of Hyogo, 2167 Shosha, Himeji, 671-2201, Japan.
Analyst. 2008 Mar;133(3):323-5. doi: 10.1039/b719089c. Epub 2008 Jan 10.
We describe a general strategy for electronic aptamer-based biosensor that is based on target-induced strand release (TISR) of a redox-modified aptamer from the aptamer-capture DNA duplex bound on an electrode.
我们描述了一种基于电子适体的生物传感器的通用策略,该策略基于氧化还原修饰的适体从结合在电极上的适体捕获DNA双链体的靶标诱导链释放(TISR)。