Tuli Karunesh, Kerndt Peter R
Los Angeles County Department of Public Health, Sexually Transmitted Disease Program, Los Angeles, California, USA.
Sex Transm Dis. 2009 Feb;36(2 Suppl):S41-8. doi: 10.1097/OLQ.0b013e3181574daa.
We assessed the cost-effectiveness of a screening, treatment, and condom provision intervention for inmates of a segregated unit for men who have sex with men at the Los Angeles County Men's Jail.
We conducted the study to determine whether the intervention provides good value for money.
We used a mathematical model to examine the effect of 10 years of intervention on sexually transmitted infections in 3 scenarios for incarcerated men who have sex with men: (a) no sex; (b) sex as before incarceration; (c) as in #2 and condom use by 20% of screened inmates. We calculated cost-effectiveness ratios as net cost per infection averted after subtracting averted treatment costs from intervention costs.
Modeling suggests that the intervention could avert 339 chlamydia, 276 gonorrhea, and 241 syphilis infections in scenario 1 (net cost $179,121); 593 chlamydia, 586 gonorrhea, and 367 syphilis infections in scenario 2 (with cost saving); and 746 chlamydia, 791 gonorrhea, 3 HIV, and 443 syphilis infections in scenario 3 (with cost saving).
Modeling indicates that the intervention can avert many sexually transmitted infections at low cost and can save costs in a scenario in which inmates continue to engage in sexual activity as they do outside jail. Modest success in efforts to promote condom use among inmates results in additional cost saving.
我们评估了一项针对洛杉矶县男子监狱中一个隔离单元内男男性行为者囚犯的筛查、治疗及提供避孕套干预措施的成本效益。
我们开展此项研究以确定该干预措施是否物有所值。
我们使用一个数学模型来检验在三种情景下,针对被监禁的男男性行为者进行为期10年的干预对性传播感染的影响:(a) 无性行为;(b) 与入狱前一样有性行为;(c) 与情景(b)相同且20%接受筛查的囚犯使用避孕套。我们通过从干预成本中减去避免的治疗成本来计算成本效益比,即每避免一例感染的净成本。
模型显示,在情景1中,该干预措施可避免339例衣原体感染、276例淋病感染和241例梅毒感染(净成本179,121美元);在情景2中,可避免593例衣原体感染、586例淋病感染和367例梅毒感染(成本节约);在情景3中,可避免746例衣原体感染、791例淋病感染、3例艾滋病毒感染和443例梅毒感染(成本节约)。
模型表明,该干预措施能够以低成本避免许多性传播感染,并且在囚犯继续像在监狱外一样进行性活动的情景下还能节约成本。在促进囚犯使用避孕套方面取得的适度成功会带来额外的成本节约。