Natali Marco, Begolo Stefano, Carofiglio T, Mistura Giampaolo
ICIS-CNR, Corso Stati Uniti 4, 35127, Padova, Italy.
Lab Chip. 2008 Mar;8(3):492-4. doi: 10.1039/b716594c. Epub 2008 Jan 31.
A new fabrication process is described allowing rapid prototyping of multilayer microfluidic chips using commercial thiolene optical adhesives. Thiolene monomer liquid is photopolymerized across transparency masks to obtain partially cured patterns supported on thin polyethylene sheets. The patterns are easily laminated and transferred to a substrate due to the elastomeric nature and adhesiveness of partially cured thiolene. The process characteristics are evaluated by realizing several test structures and fluidic chips. As an example of application, the operation of a microfluidic bead array sensor for pH measurements is then described in some detail.
