Zhao Dong, Liu Jing, Wang Wei, Zeng Zhechun, Cheng Jun, Liu Jun, Sun Jiayi, Wu Zhaosu
Department of Epidemiology, Capital Medical University Affiliated Beijing Anzhen Hospital, Beijing Institute of Heart, Lung & Blood Vessel Diseases, Anzhenli, Chaoyang District, Beijing 100029, P.R. China.
Stroke. 2008 Jun;39(6):1668-74. doi: 10.1161/STROKEAHA.107.502807. Epub 2008 Feb 28.
Epidemiological patterns of stroke may change with economic development. It is important to understand these changes for making timely strategies for stroke prevention. The aim of this study was to examine the changes in trends of stroke epidemiology during a period of fast economic development in China, based on data of the Sino-MONICA-Beijing project.
Acute stroke events were registered in a large defined population aged 25 through 74 years from 1984 to 2004. The age standardized incidence rates and case fatality rates of total stroke, ischemic stroke and hemorrhagic stroke were calculated. The trends were analyzed by a regression model.
There was a total of 14 584 stroke events registered in the study population from 1984 through 2004. The incidence rate of hemorrhagic stroke declined by 1.7% and the incidence rate of ischemic stroke increased by 8.7% annually on average. The case fatality rates significantly reduced in both types of stroke. The mean onset age of stroke was delayed by 2.7 years in men and 3.6 years in women. The proportion of deaths of cerebrovascular disease out of total deaths decreased and the proportion of ischemic heart disease increased during the study period.
Characteristics of stroke transition were found during a period of economic development in China. The changes in patterns of stroke have raised new challenges and the need for priority adjustment for stroke prevention in China.
中风的流行病学模式可能会随着经济发展而改变。了解这些变化对于制定及时的中风预防策略非常重要。本研究的目的是基于中国MONICA-北京项目的数据，研究中国经济快速发展时期中风流行病学趋势的变化。
对1984年至2004年期间年龄在25岁至74岁之间的大量特定人群中的急性中风事件进行登记。计算了总中风、缺血性中风和出血性中风的年龄标准化发病率和病死率。通过回归模型分析趋势。
1984年至2004年期间，研究人群中总共登记了14584例中风事件。出血性中风的发病率平均每年下降1.7%，缺血性中风的发病率平均每年上升8.7%。两种类型中风的病死率均显著降低。男性中风的平均发病年龄推迟了2.7岁，女性推迟了3.6岁。在研究期间，脑血管疾病死亡占总死亡的比例下降，缺血性心脏病的比例上升。
在中国经济发展期间发现了中风转变的特征。中风模式的变化带来了新的挑战，以及中国中风预防优先事项调整的必要性。
