Chen D, Román G C, Wu G X, Wu Z S, Yao C H, Zhang M, Hirsch R P
Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md 20892.
Neuroepidemiology. 1992;11(1):15-23. doi: 10.1159/000110902.
We present here the results of the Sino-MONICA-Beijing stroke study based on 700,000 Beijing residents in 1984-1986. To compare incidence rates for stroke with other communities and countries, we adopted the criteria of the WHO Collaborative Study of 17 centers which used the same definition and methodology as was used in this study. Over the 3-year period of the study, 2,593 stroke events were registered in the 25- to 74-year age-group. The incidence rate for all strokes was 189.5/100,000 and the incidence rate for first strokes was 133.6/100,000. Men had a significantly higher incidence rate than women (all strokes 219.7/100,000 for male vs. 160.5/100,000 for female, OR = 1.32, 99% limits 1.19-1.46; first strokes 151.6/100,000 for male vs. 116.4/100,000 for female, OR = 1.25, 99% limits 1.11-1.42). In comparison with other studies, age-adjusted incidence rate of stroke in Beijing was higher than in other countries, especially for hemorrhagic stroke. The proportion of hemorrhagic stroke related to other types of stroke was also higher in Beijing. Further analysis of the cases confirmed by computerized tomography also supported this finding. Unlike the incidence rates, the 4-week case fatality rate for women, 39.5%, was higher than for men, 32.8%. This finding was confirmed by a multiple logistic analysis controlling for age (p less than 0.001) and for previous stroke (p less than 0.001). The adjusted sex difference is also significant (OR = 1.37, p less than 0.001). In addition, results showed that men had a higher hospitalization rate than women. More women than men were treated at home, possibly indicating better medical care for men.
我们在此展示基于1984 - 1986年北京70万居民的中国MONICA - 北京卒中研究结果。为了将卒中发病率与其他社区和国家进行比较，我们采用了世界卫生组织17个中心协作研究的标准，该研究使用了与本研究相同的定义和方法。在研究的3年期间，25至74岁年龄组登记了2593例卒中事件。所有卒中的发病率为189.5/10万，首次卒中的发病率为133.6/10万。男性的发病率显著高于女性（所有卒中男性为219.7/10万，女性为160.5/10万，OR = 1.32，99%置信区间1.19 - 1.46；首次卒中男性为151.6/10万，女性为116.4/10万，OR = 1.25，99%置信区间1.11 - 1.42）。与其他研究相比，北京卒中的年龄调整发病率高于其他国家，尤其是出血性卒中。北京出血性卒中与其他类型卒中的比例也更高。对计算机断层扫描确诊病例的进一步分析也支持了这一发现。与发病率不同，女性4周病死率为39.5%，高于男性的32.8%。这一发现通过控制年龄（p < 0.001）和既往卒中（p < 0.001）的多因素逻辑分析得到证实。调整后的性别差异也很显著（OR = 1.37，p < 0.001）。此外，结果显示男性的住院率高于女性。在家接受治疗的女性多于男性，这可能表明男性得到了更好的医疗护理。
