[增殖性糖尿病视网膜病变患者玻璃体中的促红细胞生成素浓度]
[Erythropoietin concentrations in the vitreous body from patients with proliferative diabetic retinopathy].
作者信息
Asensio-Sánchez V M, Gómez-Ramírez V, Morales-Gómez I
机构信息
Hospital General, Medina del Campo, Valladolid, Spain.
出版信息
Arch Soc Esp Oftalmol. 2008 Mar;83(3):169-72.
OBJECTIVE
To measure erythropoietin (Epo) levels in the vitreous body from patients with proliferative diabetic retinopathy (PDR).
PATIENTS AND METHODS
Undiluted vitreous samples were obtained from 44 patients who had not undergone prior vitreous or intraocular surgery. Patients were divided into two groups: A (n= 24) patients with PDR and B (n= 20) patients with retinal detachment, preretinal macular membranes and macular holes. Epo was determined using radioimmunoassay.
RESULTS
Epo vitreous concentration in group A was 512 mU/mL (range 120-880) and in group B was 25.1 mU/mL (range 5.2-201) (p< 0.001).
CONCLUSIONS
These results show that the concentration of Epo in the vitreous body was significantly higher in patients with PDR than in the control group.
目的
测量增殖性糖尿病视网膜病变（PDR）患者玻璃体中的促红细胞生成素（Epo）水平。
患者与方法
从未接受过玻璃体或眼内手术的44例患者提供未稀释的玻璃体样本。患者分为两组：A组（n = 24）为PDR患者，B组（n = 20）为视网膜脱离、视网膜前黄斑膜和黄斑裂孔患者。使用放射免疫测定法测定Epo。
结果
A组玻璃体中Epo浓度为512 mU/mL（范围120 - 880），B组为25.1 mU/mL（范围5.2 - 201）（p < 0.001）。
结论
这些结果表明，PDR患者玻璃体中Epo的浓度显著高于对照组。
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