Abri Aghdam Kaveh, Soltan Sanjari Mostafa, Ghasemi Falavarjani Khalil
Eye Research Center, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Eye Research Center, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran; Doheny Eye Institute-UCLA, Los Angeles, CA, USA.
J Curr Ophthalmol. 2016 Mar 30;28(1):5-11. doi: 10.1016/j.joco.2016.01.008. eCollection 2016 Mar.
To review the current literature on ocular application of erythropoietin (EPO).
A comprehensive search was performed on Pubmed and Scopus databases. All selected articles were reviewed thoroughly by the authors to review current applications of the EPO in ocular diseases.
Various aspects of administration of EPO for different ischemic, traumatic, vascular, and degenerative disorders have been explained. The articles are generally preclinical with few small studies reporting clinical outcomes.
EPO has been used for the treatment of different ophthalmic conditions with promising results. Further studies are needed to elaborate the role of EPO in management of ocular diseases.
综述目前关于促红细胞生成素(EPO)眼部应用的文献。
对PubMed和Scopus数据库进行全面检索。作者对所有入选文章进行了深入审查,以回顾EPO在眼部疾病中的当前应用。
已阐述了EPO用于不同缺血性、创伤性、血管性和退行性疾病的给药各个方面。这些文章大多为临床前研究,仅有少数小型研究报告了临床结果。
EPO已用于治疗不同的眼科疾病,取得了有前景的结果。需要进一步研究以阐明EPO在眼部疾病管理中的作用。