Lotta S, Scelsi R, Alfonsi E, Saitta A, Nicolotti D, Epifani P, Carraro U
Centro di Recupero G. Verdi, USL.3., Pavia, Italy.
Paraplegia. 1991 May;29(4):247-52. doi: 10.1038/sc.1991.35.
Morphometric and electrophoretic properties of soleus and medialis gastrocnemius fibres from paraplegic patients were studied 1 to 10 months following complete traumatic cord transection (spinal cord level C5-T1). In the short term of paraplegia (1-6 months) gastrocnemius medialis and soleus muscles showed predominant atrophy of IIA fibre types. In long term paraplegia (8-10 months) atrophy and reduction of type 1 fibres, with presence of high percentages of type IIB fibres, were seen in both studied muscles. The consistence in both muscles of IIB intermediate fibres in long term paraplegia, seems to indicate the initial stage of a mechanism of fibre transformation reflecting the adaptative capacity of the paretic muscle to spasticity. Electrophysiological studies of the H-reflex and the H/M ratio values reveal an increase of the H-reflex excitability in the soleus and gastrocnemius muscles during a 1 to 10 months follow-up.
对完全性创伤性脊髓横断（脊髓节段C5 - T1）后1至10个月的截瘫患者比目鱼肌和腓肠肌内侧头纤维的形态计量学和电泳特性进行了研究。在截瘫短期（1 - 6个月），腓肠肌内侧头和比目鱼肌表现出IIA型纤维为主的萎缩。在截瘫长期（8 - 10个月），在两块被研究肌肉中均可见1型纤维萎缩和减少，伴有高比例IIB型纤维。长期截瘫时两块肌肉中IIB中间纤维的一致性，似乎表明了纤维转化机制的初始阶段，反映了瘫痪肌肉对痉挛的适应能力。对H反射和H/M比值的电生理研究显示，在1至10个月的随访期间，比目鱼肌和腓肠肌的H反射兴奋性增加。
