一项保守性打鼾治疗方法的随机交叉试验：下颌重新定位矫治器与鼻持续气道正压通气
A randomized crossover trial of conservative snoring treatments: mandibular repositioning splint and nasal CPAP.
作者信息
Robertson Stuart, Murray Maria, Young David, Pilley Richard, Dempster John
机构信息
Department of Otolaryngology, Head and Neck Surgery, Crosshouse Hospital, Kilmarnock, Scotland, UK.
出版信息
Otolaryngol Head Neck Surg. 2008 Mar;138(3):283-288. doi: 10.1016/j.otohns.2007.11.004.
OBJECTIVE
To compare the effectiveness of a mandibular repositioning splint (MRS) and nasal continuous positive airway pressure (CPAP) device as first-line treatments for disruptive snoring.
STUDY DESIGN
Prospective randomized crossover trial.
SUBJECTS AND METHODS
Twenty snorers received 3 months of treatment with both an MRS and nasal CPAP. Snoring Outcomes Survey (SOS), Snoring Bed Partner Survey, and Epworth questionnaires were completed serially. Changes in questionnaire scores were analyzed with a general linear statistical model and by analysis of variance.
RESULTS
There was a significant difference between the three preference outcomes for the mean SOS changes (P = 0.003). The mean SOS change was significantly greater for those who preferred MRS to CPAP (mean score difference, 27.15). Eight snorers chose final long-term MRS treatment, five chose nasal CPAP, and seven chose neither.
CONCLUSION
The majority of disruptive snorers can be managed effectively with conservative treatments and therefore avoid surgery.
目的
比较下颌重新定位矫治器（MRS）和鼻持续气道正压通气（CPAP）设备作为治疗阻塞性打鼾一线治疗方法的有效性。
研究设计
前瞻性随机交叉试验。
对象与方法
20名打鼾者接受了为期3个月的MRS和鼻CPAP治疗。连续完成打鼾结果调查（SOS）、打鼾床伴调查和爱泼沃斯问卷。问卷分数的变化采用一般线性统计模型和方差分析进行分析。
结果
三种偏好结果的平均SOS变化之间存在显著差异（P = 0.003）。对于那些更喜欢MRS而非CPAP的人，平均SOS变化显著更大（平均分数差异为27.15）。8名打鼾者选择了最终的长期MRS治疗，5名选择了鼻CPAP，7名两者都未选择。
结论
大多数阻塞性打鼾者可以通过保守治疗得到有效管理，从而避免手术。
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